Plasmin Activation of Glial Cells through Protease-Activated Receptor 1
Figure 6
Effect of antifibrinolytics on plasmin induced glial cell detachment. A172 cells were stimulated with plasmin generated in situ from plasminogen (5 U/mL) and streptokinase (50 KU/mL) in the presence of aprotinin or ε-aminocaproic acid. Cell detachment was expressed in arbitrary units defined in Section 2. Results were expressed as the median ± interquartile range (IQR) from experiments. Rest = Resting; Pls = plasmin; Apr = aprotinin (200 KIU/mL); EACA = ε-aminocaproic acid (10 mmoles/L).
