Specimens from Biopsies of Colorectal Polyps Often Harbor Additional Diagnoses

Table 3

Additional diagnoses detected at colorectal biopsy for polyps.

Additional diagnoses	Factors potentially contributing to diagnostic difficulty
Mucosal prolapse	Only small focus affected
Melanosis coli	Nonpolypoid mucosa preferentially affected
	Polyps relatively or completely spared
Eosinophilic colitis	Confusion with reaction to adenoma
	Clinically occult
Schistosomiasis	Minute ova
	Affected nonpolypoid mucosa otherwise normal or focally normal
	Clinically occult
Intestinal spirochetosis	Minute bacteria
	Confined to nonpolypoid mucosa
	Affected nonpolypoid mucosa otherwise normal
	Clinically occult