Immunoreactivity of the 14F7 Mab Raised against N-Glycolyl GM3 Ganglioside in Primary Lymphoid Tumors and Lymph Node Metastasis
Figure 3
Microphotographs of the 14F7 Mab reaction in lymph node metastasis. (a) and (b): Hematoxylin and eosin staining of lymph node metastasis of breast ductal and lobular adenocarcinomas, respectively. (c) and (d): Immunostaining with 14F7 Mab. Observe: an intense reaction of 14F7 Mab located in both cell membrane and cytoplasm of malignant epithelial cells. See: an intense immunostaining in lymphocytes of tumor adjacent areas (c) (red arrows). Inset on the upper-right corner, 400x magnification. Note: the absence of reactivity in peritumoral lymphocytes (d). (e) and (f): Negative controls. Observe: the lack of staining. White bar = 100 μm.
