Research Article

Immunoreactivity of the 14F7 Mab Raised against N-Glycolyl GM3 Ganglioside in Primary Lymphoid Tumors and Lymph Node Metastasis

Figure 4

Microphotographs of the 14F7 Mab staining in lymph node metastasis. (a) and (b): Hematoxylin and eosin staining of lymph node metastasis of colonic and lung adenocarcinomas, respectively. (c) and (d): Immunoreactivity of the 14F7 Mab. Observe: an intense reaction of 14F7 Mab located in both cell membrane and cytoplasm of malignant epithelial cells. See: a moderate immunostaining in lymphocytes of tumor adjacent areas (red arrows). Inset on the upper-right corner, 400x magnification. (e) and (f): Negative controls. Observe: the lack of staining. White bar = 100 μm.
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