Prognostic Significance of N-Glycolyl GM3 Ganglioside Expression in Non-Small Cell Lung Carcinoma Patients: New Evidences

<div>HP-TLC of glycolipids fraction isolated from FFPE samples of NSCLC. (a) Chemical staining with orcinol. 1 and 2: purified controls of NeuAcGM3 and NeuGcGM3, respectively. 3–5: glycolipids fraction extracted from NSCLC samples. Note the expression of both NeuAcGM3 and NeuGcGM3 gangliosides. (b) TLC-immunostaining using 14F7 Mab. Observe that the 14F7 Mab only reacted with the NeuGc-containing variant of GM3 ganglioside.</div>

Pathology Research International

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Figure 2

Figure 2: Prognostic Significance of N-Glycolyl GM3 Ganglioside Expression in Non-Small Cell Lung Carcinoma Patients: New Evidences 