Research Article
Predictive Response Value of Pre- and Postchemoradiotherapy Variables in Rectal Cancer: An Analysis of Histological Data
Table 3
Pathological parameters.
| | Variable | (%) |
| | ypT stage | | | pT0-1 | 38 (22.8) | | pT2–4 | 129 (77.2) | | ypN stage | | | pN0 | 110 (65.9) | | pN1-2 | 57 (34.1) | | Pathological stage | | | 0 | 58 (34.7) | | II | 58 (34.7) | | III | 51 (30.5) | | T downstaging | | | Yes | 67 (40.1) | | No | 100 (59.9) | | Pathological TNM downstaging | | | Yes | 95 (56.9) | | No | 72 (43.1) | | CRM distance | | | >2 mm | 159 (95.2) | | ≤2 and >1 mm | 8 (4.8) | | Mandard TRG | | | TRG1-2 (good responders) | 85 (50.9) | | TRG3–5 (bad responders) | 82 (49.1) | | Other characteristics of resected specimen | | | Grade | | | 0 | 32 (19.2) | | 1 | 31 (18.6) | | 2 | 98 (58.7) | | 3 | 6 (3.6) | | Mucinous presence | | | Yes | 41 (24.5) | | No | 126 (75.4) | | Inflammatory infiltrate | | | Scarce | 60 (35.9) | | Moderated | 75 (44.9) | | Marked | 28 (16.8) | | Missing | 4 (2.4) | | Desmoplastic reaction | | | Scarce | 45 (26.9) | | Moderated | 64 (38.3) | | Marked | 51 (30.5) | | Missing | 7 (4.2) | | Necrosis grade | | | Scarce | 27 (16.2) | | Moderated | 38 (22.8) | | Marked | 99 (59.3) | | Missing | 3 (1.8) | | Mitosis number | | | ≤9.5 | 73 (43.7) | | >9.5 | 68 (40.7) | | Missing | 26 (15.6) | | Lymphatic permeation | | | No | 100 (59.9) | | Yes | 67 (40.1) | | Vascular permeation | | | No | 142 (85) | | Yes | 25 (15) | | Perineural permeation | | | No | 96 (57.5) | | Yes | 71 (42.5) | | Distal margin | | | ≥2 cm | 108 (65.7) | | <2 cm and ≥1 cm | 59 (35.3) |
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