A Novel Model of Cancer-Induced Peripheral Neuropathy and the Role of TRPA1 in Pain Transduction

Figure 2

Light micrographs of the longitudinal sections of the sciatic nerve. (a) SNs of sham-operated animals show normal fascicles and a wavy pattern of the intact fibers which characterize normal nerves. (b–e) SNs of cancer-injected animals (at days 3, 7, 14, and 21, resp.) show a gradual invasion of cancer cells accompanied by a degradation of the nerve fibers. SNs are stained by hematoxylin and eosin (×20). Scale bars = 100 μm.

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