Table 1: Colonic myeloperoxidase (MPO) tissue levels 1 week after intracolonic (i-colo) TNBS; effect of concomitant ceftriaxone (CTX).

Treatment (n)Mean ± SEM (units/mg)

1 wk veh + i-colo veh [22] 0 . 2 3 ± 0 . 0 5
1 wk CTX + i-colo veh [22] 0 . 1 8 ± 0 . 0 3
1 wk veh + i-colo TNBS [13] 0 . 5 1 ± 0 . 0 4 a
1 wk CTX + i-colo TNBS [13] 0 . 2 3 ± 0 . 0 4 b

One-week CTX treatment (200 mg/Kg/day (302 μmole), ip) attenuated colonic inflammation caused by intracolonic (i-colo) TNBS instillation, as measured by MPO activity. a 𝑃 < 0 . 0 0 5 compared to 1-week veh + i-colo veh; b 𝑃 < 0 . 0 0 5 compared to 1-week veh + i-colo TNBS).