Table 2: Colonic myeloperoxidase (MPO) issue levels 1 week after intracolonic TNBS; effect of concomitant cephalothin (CLT).

Treatment ( 𝑛 )Mean ± SEM (units/mg)

1 wk veh + i-colo veh [23] 0 . 2 4 ± 0 . 0 3
1 wk CLT + i-colo veh [23] 0 . 2 3 ± 0 . 0 3
1 wk veh + i-colo TNBS [23] 0 . 5 6 ± 0 . 0 9 a
1 wk CLT + i-colo TNBS [23] 0 . 2 9 ± 0 . 0 4 b

One-week cephalothin treatment ((302 μmole) 126 mg/Kg/day, ip) was effective to attenuate colonic inflammation caused by intracolonic (ic) TNBS instillation, as measured by MPO activity. a 𝑃 < 0 . 0 0 5 compared to 1-week veh + ic veh; b 𝑃 < 0 . 0 0 5 compared to 1-week veh + ic TNBS).