Table 1:
Effect of lercanidipine in various doses on Tail flick latency (second) in paclitaxel-induced neuropathic rats. Data are expressed as mean ± SD.
Day
Control (
)
Paclitaxel 1 mg/kg (
)
Lercanidipine 0.5
μ
g/kg (
)
Lercanidipine 1.0
μ
g/kg (
)
Lercanidipine 2.5
μ
g/kg (
)
0
7
14
*
*
21
*
*
28
compared to 0 day,
compared to paclitaxel group.