Research Article
The Effect of Topical Local Anesthetics on Thermal Pain Sensitivity in Patients with Irritable Bowel Syndrome
Table 1
Testing and treatment conditions over 7 nonconsecutive sessions. The seven sessions were spread out over two weeks, typically with 4 sessions during the first and 3 sessions during the second week. Following a training session, baseline sessions were assessed on sessions 2, 5, and 7. The fifth and seventh sessions were used to assess carryover effects of the treatment conditions. Treatment sessions were carried out on sessions 3, 4, and 6, which included a combination of rectally and orally administered anesthetic (i.e., lidocaine) and placebo. The order of anesthetic and placebo were not random. The anesthetic was administered either rectally (session 4) or orally (session 6) while the other site was given a placebo (i.e., oral placebo on session 4, rectal placebo on session 6).
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