Table 2: Assessments used to evaluate fibromyalgia symptom severity in medication trials.

SymptomMedication used in treatment trials
PregabalinDuloxetineMilnacipranSodium oxybate

FatigueMAFMFIMFIFatigue VAS
FibrofogMASQ
SleepMOS-SleepJSS, MOS-sleepFOSQ, JSS
DepressionBDI, HADS-DBDI-II, HAMD17BDI
AnxietyHADS-ABeck Anxiety Inv.Beck anxiety inv.
PainPain VAS, Pain NRSBPI-mod short formPain VAS, McGill pain quest.Pain VAS
Physical disabilityFIQ, F-HAQFIQ, SDSFIQ, MDHAQFIQ
Global/QOLFIQ, CGI-C, PGI-C, SF-36EQ-5D, FIQ, CGI-S, PGI-I, SF-36FIQ, PGI-C, SF-36FIQ, CGI-C, CGI-S, PGI-C, SF-36
TendernessMTPS-FISTPI

BDI: beck depression inventory, BPI: brief pain inventory, CGI-C: clinician global impression of change, CGI-S: clinician global impression of severity, EQ-5D: EUROQOL 5-D qUESTIONNAIRE, F-HAQ: fibromyalgia health assessment questionnaire, FIQ: fibromyalgia impact questionnaire, FIS: fibromyalgia intensity scale, FOSQ: Functional outcomes of sleep questionnaire, HADS: hospital anxiety and depression scale (-D denotes depression subscale, -A denotes anxiety subscale), HAMD17: 17-item hamilton rating scale for depression, Inv.: inventory, JSS: jenkins sleep scale, MAF: multidimensional assessment of fatigue, MASQ: multiple abilities self-report questionnaire, MDHAQ: multi-dimensional health assessment questionnaire, MFI: multidimensional fatigue inventory, MOS-sleep: medical outcomes studies sleep scale, MTPS: manual tender point survey, NRS: numeric rating scale, PGI-C: patient global impression of change, PGI-I: patient global impression of improvement, QOL: quality of life, QUEST.: questionnaire, SDS: sheehan disability scale, SF-36: short form health survey, TPI: tender point index, VAS: visual analogue scale.