817347.fig.001a
(a)
817347.fig.001b
(b)
817347.fig.001c
(c)
Figure 1: (a) Representative traces of pH currents recorded in DRG neurons innervating muscle. (b) The percentage of labeled muscle DRG neurons that responded to pH 5 application with a transient inward current (ASIC-like current) greater than 100 pA is shown for each experimental group. (c) The mean cell diameters of the muscle DRG neurons that responded to pH 5 application with a transient ASIC-like current (responders; black bars) are compared to those that did not respond (nonresponders; open bars) for each of the experimental groups. The number of responders in each group is as follows: uninjected = 29/57; Injection 1, pH 7.2 = 19/29; Injection 1, pH 4.0 = 22/35; Injection 2, pH 7.2 = 25/48; Injection 2, pH 4.0 = 24/36. .