Research Article

Interaction between Mu and Delta Opioid Receptor Agonists in an Assay of Capsaicin-Induced Thermal Allodynia in Rhesus Monkeys

Figure 2

Antiallodynic effects of morphine (a) or nalbuphine (b) administered alone or in a mixture with SNC80. Abscissae: dose morphine or nalbuphine in mg/kg (log scale). Ordinates: percent maximum possible effect (%MPE). All points show data from 3 monkeys. ED50 values are compared in Table 1, and data in each panel were analyzed by 2-way ANOVA (see text for details). The asterisk in the right panel indicates a significant difference from nalbuphine alone.
867067.fig.002a
(a)
867067.fig.002b
(b)