A New Drug Release Method in Early Development of Transdermal Drug Delivery Systems

<table>The effect of amount of moisture on the SSS on the drug release rate of Durogesic patches (12 <i>μ</i>g/hr (a); 75 <i>μ</i>g/hr (b)). The error bars denote the confidential interval (<svg height="11.125" id="M13" style="vertical-align:-0.1638pt" version="1.1" viewbox="0 0 36.237499 11.125" width="36.237499" xmlns="http://www.w3.org/2000/svg" xmlns:xlink="http://www.w3.org/1999/xlink">
<g transform="matrix(.017,-0,0,-.017,.062,10.862)"><path d="M495 86q-46 -47 -87 -72.5t-63 -25.5q-43 0 -16 107l49 210q7 34 8 50.5t-3 21t-13 4.5q-35 0 -109.5 -72.5t-115.5 -140.5q-21 -75 -38 -159q-50 -10 -76 -21l-6 8l84 340q8 35 -4 35q-17 0 -67 -46l-15 26q44 44 85.5 70.5t64.5 26.5q35 0 10 -103l-24 -98h2
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</svg>) and are shown where they exceed the dimensions of the symbols.</table>

Pain Research and Treatment

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Figure 2

Figure 2: A New Drug Release Method in Early Development of Transdermal Drug Delivery Systems 