Loss of Central Inhibition: Implications for Behavioral Hypersensitivity after Contusive Spinal Cord Injury in Rats
Figure 2
Manifestation of allodynia on the cutaneous surface of the back over time after contusive SCI. Before injury, the force required to elicit a response was equal at all points. Within 9 days after the contusion, the force was reduced 4-5-fold in all areas, with the epicenter (level 0) showing the greatest hypersensitivity. This same pattern persisted up to 90 days after SCI. Overall, a 10-fold increase in tactile allodynia was observed on the back of the animals with SCI. The data are expressed as means.
