Skin Needling to Enhance Depigmenting Serum Penetration in the Treatment of Melasma

Table 2

	Depigmenting Serum + Skin needling		Depigmenting serum alone
Pz.	L* before treatment	L* after treatment	L* before treatment	L* after treatment
1	51.70	59.89	54.80	59.94
2	55.82	65.49	55.36	60.88
3	58.45	68.22	56.77	64.89
4	54.27	64.17	56.67	63.74
5	48.85	59.63	53.15	59.55
6	59.78	70.92	61.18	62.18
7	55.09	66.30	53.92	60.97
8	52.10	63.70	51.20	57.66
9	56.73	69.27	58.18	65.52
10	56.34	67.18	59.48	65.02
11	51.45	62.02	54.54	60.55
12	60.15	70.38	59.76	66.61
13	52.60	63.70	54.39	60.03
14	56.25	64.22	56.10	59.00
15	55.91	66.10	56.83	62.03
16	50.26	65.35	55.92	59.62
17	52.73	59.73	52.13	60.79
18	50.35	64.71	51.17	59.22
19	52.72	62.71	54.73	62.14
20	55.31	65.73	52.04	61.98
Average	54.34	64.97	55.42	61.61
D STD	3.2665	3.1710	2.8177	2.425