Review Article

Mobilisation versus Bed Rest after Skin Grafting Pretibial Lacerations: A Meta-Analysis

Table 1

Primary and secondary outcomes.

Study detailsStudiesPatientsOdds ratio (95% CI)

Primary outcomes
 Graft healing at 7 daysRCTs21360.86 (0.29–2.56)
 Graft healing at 7 daysRCTs + CS31660.86 (0.29–2.56)
 Graft healing at 14 daysRCTs trauma patients [24]31450.86 (0.29–2.56)
 Graft healing at 14 daysRCTs all patients [24]31860.74 (0.31–1.79)
 Graft healing at 14 daysRCTs + CS trauma patients [24]41760.86 (0.29–2.56)
 Graft healing at 14 daysRCTs + CS all patients [24]42160.74 (0.31–1.79)

Secondary outcomes
 Reduction in mobilityRCT1470.06 (0.00–1.14)
 Reduction in mobilityRCT, worst case scenario [47]1610.94 (0.27–3.22)
 Reduction in mobilityRCT, best case scenario [47]1610.03 (0.00–0.45)
 HaematomaRCT1610.95 (0.08–11.13)
 Heparin coagulopathyRCT1610.61 (0.02–15.69)
 Graft infectionRCT1610.95 (0.08–11.13)
 Delayed healing versus corticosteroidsRCT1758.20 (0.99–15.41)
 Healing time versus anaesthesiaRCT175−4.60 (−10.88–1.68)
 Donor site healingRCT175−0.50 (−2.88–1.88)

Abbreviations: RCT, randomised controlled trials; CS, cohort study.