Preliminary Analysis of the Nonsynonymous Polymorphism rs17563 in BMP4 Gene in Brazilian Population Suggests Protection for Nonsyndromic Cleft Lip and Palate

Table 2

The genotype and allele distribution of rs17563 in nonsyndromic CL±P patients and controls and result of logistic regression.

SNP rs17563		Controls; 𝑛 (%)	Cases; 𝑛 (%)	𝜒^2	𝑃	OR	95% CI
Genotype	TT^1	52 (21,1)	49 (39,8)	—	—	1.00	—
	TC	130 (52,8)	53 (43,1)	10.645	0.00110	0.43	0.26–0.71
	CC	64 (26,1)	21 (17,1)	11.217	0.00081	0.35	0.19–0.66
Allele	T^1	234 (47,6)	151 (61,4)	—	—	1.00	—
	C	258 (52,4)	95 (38,6)	13.992	0.00018	0.40	0.25–0.65

¹Reference factor.