Review Article

Complements and the Wound Healing Cascade: An Updated Review

Figure 3

Cutaneous wound healing in time. A schematic representation of cutaneous wound healing and the growth factors and cellular participants in the first 72 hours of injury. The complement cascade appears to be involved in many stages of the wound healing. Platelets, macrophages, fibroblasts, and the formation of the fibrin clot are the major cellular players in early cutaneous, tendon, ligament, muscle, and bone healing.
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