Review Article

The Role of Current Techniques and Concepts in Peripheral Nerve Repair

Table 1

Neurosensory impairment classification according to Sunderland and Seddon.

Classification of nerve injury
SunderlandSeddonInjuryNeurosensory impairmentRecovery potential

INeuropraxiaIntrafascicular oedema, conduction blockNeuritis, paresthesiaFull (1 day to 1 week)
Possible segmental demyelinationNeuritis, paresthesiaFull (1 to 2 months)

IIAxon severed, endoneurial tube intactParesthesia, episodic dysesthesiaFull (2 to 4 months)

IIIAxonotmesisEndoneurial tube tornParesthesia, dysesthesiaSlow, incomplete (12 months)

IVOnly epineurium intactHypoesthesia, dysesthesia, and neuroma formationNeuroma in continuity

VNeurotmesisLoss of continuityAnaesthetic, intractable pain, and neuroma formationNone

VICombination of aboveCombination of aboveUnpredictable