An Insight into the Sialomes of Bloodsucking Heteroptera

Table 1

Molecularly and functionally characterized salivary components of bloodfeeding Hemiptera.

Name	Family	Insect	Activity	Notes	Reference
Prolixin	Nitrophorin	Rhodnius prolixus	Anticlotting	FXa inhibitor	[2]
RPAI	Lipocalin	R. prolixus	Antiplatelet	Binds ADP	[3, 4]
Nitrophorins	Nitrophorin	R. prolixus	Antihistamine	Binds histamine, carrier of NO	[5, 6]
BABP	Nitrophorin	R. prolixus	Antiserotonin	Binds serotonin	[7]
Inositol phosphatase	Inositol phosphatase	R. prolixus	Inositol phosphatase	Unknown function	[8]
Lysophosphatidylcholine	Lipid	R. prolixus	Antihemostatic		[9]
NO	Inorganic gas	R. prolixus, Cimex lectularius	Vasodilatory, antiplatelet	Activates guanylate cyclase	[10, 11]
Apyrase	5^′-nucleotidase	Triatoma infestans	Antiplatelet	Destroys ADP	[12, 13]
Triplatin	Lipocalin	T. infestans	Antiplatelet, vasodilator	TXA2 binder	[14, 15]
Triafestin	Lipocalin	T. infestans	Anticlotting, antipain	Inhibits FXII activation	[16]
Trialysin	Trialysin	T. infestans	Antimicrobial	Pore forming	[17, 18]
Pallidipin	Lipocalin	T. pallidipennis	Antiplatelet	Collagen inhibitor (possible TXA2 binder)	[19, 20]
Triabin	Lipocalin	T. pallidipennis	Anticlotting	Anti-thrombin	[21–23]
Procalin	Lipocalin	T. protracta	Allergen	Function unknown	[24]
Dipetalodipin	Lipocalin	Dipetalogaster maxima	Antiplatelet, vasodilator	TXA2 binder	[25]
Apyrase	Cimex apyrase	Cimex lectularius	Antiplatelet	Destroys ADP	[26]
Nitrophorin	Inositol phosphatase	C. lectularius	Antiplatelet, vasodilator	Carrier of NO	[27–29]
Fibrinolytic enzyme	Serine proteinase	Panstrongylus megistus	Anticlotting		[30]