821591.fig.002
Figure 2: Comparative genome architecture of SINV-1, SINV-2, and SINV-3. Orientation of each genome is 5′ to 3′ (left to right). Relative positions of non-structural and structural proteins are indicated within each open reading frame (rectangles). ORFs are illustrated in different vertical positions to show their in-frame, comparative relationships. The SINV-1 genome is monopartite, dicistronic, and possesses 6 copies of the viral protein genome (VPg) peptide, an intergenic IRES, a predicted overlapping gene (pog) within ORF 2, and well-characterized capsid proteins (VPs) of known mass. The SINV-2 genome is monopartite with non-structural proteins encoded by the 3′-proximal ORF. The 3 small ORFs at the 5′-proximal end of the genome are presumed capsid proteins. The SINV-3 genome is monopartite with non-structural proteins encoded by ORF 1 (5′-proximal) and capsid proteins by ORF 2 (3′-proximal). An overlapping ORF (Arg) was identified within ORF 2 of a virus isolate from infected S. invicta ants from Argentina.