Sex Differences and Menstrual Cycle Phase-Dependent Modulation of Craving for Cigarette: An fMRI Pilot Study

Table 1

Cerebral activations of male and female participants during viewing of craving images (relative to neutral images). R = right; L = left; BA = Brodmann area; is uncorrected at 0.001.

Brain region	R/L	BA	MNI coordinates			-scores
			Males
Frontal superior medial	L	9	−4	52	14	3.48
Anterior cingulate	L	9	−10	46	10	3.30
Insula	L	—	−35	10	−7	3.38	30
Frontal superior	L	9	−21	56	24	3.19	51
Putamen	L	—	−28	0	14	3.17	28
Females
Anterior cingulate	L	24	0	38	−7	3.27	29
Precuneus	L	23	−7	−60	21	3.10	40

  results remained significant after application of cluster threshold as determined by Monte Carlo simulation; of the same cluster.