Clinical Study

Sex Differences and Menstrual Cycle Phase-Dependent Modulation of Craving for Cigarette: An fMRI Pilot Study

Table 2

Cerebral activations of female participants, during viewing of appetitive cigarette images (relative to neutral images) and during the follicular and luteal menstrual cycle phases. R = right; L = left; BA = Brodmann area; value is uncorrected at 0.001.

Brain regionR/LBAMNI coordinates-scoresVoxels

Follicular phase
 Angular
R3949−66324.6287
 Posterior cingulateL31−4−49323.98241
 Anterior cingulateR24435−73.4577
 Inferior temporalR1946−70−43.40
 PrecuneusL29−7−49103.29
 AngularL39−49−66383.2150
 Medial superior frontalL8−446323.2033
 MidcingulumL310−28423.04
Luteal phase
 HippocampusR42−35−103.36

results are no longer significant after applying the cluster threshold as determined by Monte Carlo simulation.