Review Article
Chronic Traumatic Encephalopathy: A Review
Table 4
Clinicopathological correlations [
5].
| Damage area | Clinical presentation |
| Hippocampus Entorhinal cortex Medial thalamus | Early deficits in memory |
| Frontal cortex and underlying white matter | Dysexecutive symptoms |
| Dorsolateral parietal Posterior temporal Occipital cortices | Visuospatial difficulties |
| Substantia nigra Pars compacta | Parkinsonian motor features |
| Cortical and subcortical frontal damage Cerebellar tract injury in brainstem | Gait disorder: staggered, slowed, ataxic |
| Brainstem nuclei (hypoglossal/oculomotor) | Dysarthria, dysphagia, ocular abnormalities |
| Amygdala | Aggression and violent outbursts |
|
|