Research Article
Exercise-Induced Functional Changes in People with Parkinson’s Disease following External Cueing and Task-Based Intervention
Table 3
Participant clinical outcomes.
| | Measure | Participant
1
score () | Participant
2
score () | Participant
3
score () | Participant
4
score () | Participant 5
score () | Participant 6
score () | Participant
7
score () | Participant
8
score () | Participant
9
score () |
| | UPDRS-III | Base | 15 | 28 | 15 | 25 | 26 | 28 | 50 | 29 | 26 | | EOT | 11 (-4) | 29 (1) | 15 (0) | 17 (-8) | 16 (-10) | 38 (10) | 36 (-14) | 16 (-13) | 40 (14) | | EOT+4 | 9 (-6) | 22 (-6) | 7 (-8) | 19 (-6) | 18 (-8) | 35 (7) | 52 (2) | 15 (-14) | 17 (-9) |
| | MiniBEST | Base | 26 | 24 | 26 | 19 | 15 | 22 | 12 | 13 | 22 | | EOT | 27 (1) | 24 (0) | 26 (0) | 18 (-1) | 23 (8) | 22 (0) | 8 (-4) | 18 (5) | 23 (1) | | EOT+4 | 27 (1) | 26 (2) | 26 (0) | 19 (0) | 22 (7) | 23 (1) | 8 (-4) | 18 (5) | 25 (3) |
| Gait Speed
(m/s) | Base | 1.372 | 0.911 | 1.524 | 0.914 | 0.768 | 0.951 | 0.418 | 0.646 | 1.301 | | EOT | 1.49 (0.12) | 1.11 (0.2) | 1.28 (-0.25) | 1.0 (0.08) | 0.9 (0.11) | 1.0 (0.05) | 0.57 (0.15) | 0.9 (0.25) | 1.27 (-0.03) | | EOT+4 | 1.32 (-0.06) | 1.05 (0.14) | 1.33 (-0.2) | 1.03 (0.11) | 0.99 (0.22) | 1.0 (0.05) | 0.26 (-0.16) | 0.83 (0.18) | 1.38 (0.08) |
| | ABC | Base | 98.75 | 74.69 | 87.5 | 68.75 | 70 | 83.75 | 54.38 | 49.38 | 86.88 | | EOT | 96.88
(-1.88) | 88.13
(13.44) | 96.88
(9.38) | 80.63
(11.25) | 64.38
(-5.62) | 83.13
(-0.62) | 80.63
(26.25) | 65
(15.63) | 80.63
(-6.25) | | EOT+4 | 99.38
(0.62) | 85 (10.31) | 96.56
(9.06) | 69.06
(16.88) | 74.38
(4.38) | 82.5
(-1.25) | 69.06
(14.69) | 70
(20.63) | 91.25
(4.38) |
| | PDQ-SI | Base | 9.6 | 14.7 | 5.1 | 15.4 | 24.4 | 31.4 | 35.3 | 38.5 | 17.9 | | EOT | 5.8 (-3.8) | 17.3 (2.6) | 1.3 (-3.8) | 16 (0.6) | 30.8 (6.4) | 31.1 (0.7) | 26.9 (-8.4) | 34 (-4.5) | 16.7 (-1.2) | | EOT+4 | 5.1
(-4.5) | 10.9
(-3.8) | 3.2
(-1.9) | 12.2
(-3.2) | 12.8
(-11.6) | 34
(2.6) | 41
(5.7) | 32.7
(-5.8) | 15.4
(-2.5) |
|
|
Abbreviations: = change from baseline; ABC = Activities-specific Balance Confidence scale; EOT = end of treatment; EOT+4 = end of treatment +4 weeks; MCID = minimal clinical important difference; MDC = minimal detectable change; MiniBEST = MiniBEST test; PDQ-SI = Parkinson’s Disease Quality of Life Summary Index; UPDRS III = Unified Parkinson’s Disease Rating Scale Part III Motor. Note: italic = improvement meeting minimal clinical important difference (MCID) or minimal detectable change (MCD). |
