| | at 3 T
| at 3 T
| hepatic LIC in mg/g | Ferritin (mode) | Liver biopsy LIC mg/g dry weight | Documented transfusion iron loading mg/kg | Duration of chronic transfusion in years | ALT | Chelation | Clinical correlation |
| 1 | 17.4 | 57.5 | 1.1 | <750 | | <100 | NA | N | NI | F, TIL | 2 | 14.9 | 67.1 | 1.2 | <750 | | <100 | NA | N | NI | F, TIL | 3 | 14.6 | 68.3 | 1.2 | <750 | | <100 | NA | N | NI | F, TIL | 4 | 14.7 | 73.2 | 1.3 | <750 | | <100 | NA | N | NI | F, TIL | 5 | 12.9 | 77.3 | 1.3 | <750 | | <100 | NA | N | NI | F, TIL | 6 | 11.3 | 88.2 | 1.5 | <750 | | <100 | NA | N | NI | F, TIL | 7 | 7.4 | 135.1 | 2.1 | <750 | | <100 | NA | N | NI | F, TIL | 8 |
7.3 | 137.0 | 2.1 | 1500–2250 | | <100 | NA | | NI | TIL | 9 | 5.5 | 183.5 | 2.7 | 2250–3000 | | <100 | 1 | N | NI | TIL, ferritin 1 year. after chronic transfusion were 6000, and followup was 5 mg/g | 10 | 5.7 | 176.5 | 2.6 | 750–15.00 | 2.5 | >100, switched to HU | 1 | N | Phlebotomy | B (within 6 months), F | 11 | 4.8 | 208.3 | 3 | 750–1500 | | >100 (exchange transfusions) | 6 | N | Y | F, TIL | 12 | 3.7 | 270.3 | 3.8 | 2250–3000 | | >100 (only exchange transfusions) | 2 | N | Y | TIL | 13 | 2.9 |
344.8 | 4.7 | 750–1500 | |
>100, | 1 | | N | F, received 12 monthly transfusions for one year, discontinued a year prior | 14 | 2.5 | 400.0 | 5.4 | 2250–3000 | | >100, | 4 | N | Y | | 15 | 1.7 | 600.0 | 8 | 2250–3000 | 6.3 | >100, | 2 | N | N | B (within 6 months), | 16 | 1.6 | 625.0 | 8.3 | 2250–3000 | 14.2 | >100, | 4 | N | Y, | F, and ALT. Poor compliance | 17 | 1.57 | 635.0 | 8.4 | >3000 | | >100, | 5 | Y | N | F, repeat a year after chelation 6.9 | 18 | 1.2 | 833.3 | 10.9 | >3000 | | >100, | 9 | Y | Y | F, ALT LFTs improved after he started on exchange, poor compliance | 19 | 0.8 | 1304.3 | 16.9 | 2250–3000 | 24 | >100, switched to HU | 11 | N | Phlebotomy | B done 1.5 years prior, after which patient switched to HU | 20 | | | Extreme iron overload | 6–8000 | | >100, | 15 | Y | Y | F, ALT, and poor compliance | 21 | | | Extreme iron overload |
>10.000 | 32 | >100, | 16 | Y | Contraindicated due to toxicity | B (3 years prior), F, | 22 | | | Extreme iron overload | 8–1100 | | >100, | 8 | Y | Y | F, ALT Poor compliance |
|
|