Clinical Study
FDG-PET/CT Imaging Predicts Histopathologic Treatment Responses after Neoadjuvant Therapy in Adult Primary Bone Sarcomas
Table 1
Patient characteristics and imaging findings.
| | Subtypes | Location | Age | Sex | Baseline | End of treatment | Metabolic response (decrease 60%) | Necrosis | SUVmax | Size | SUVmax | Size |
| 1 | Ewing’s Sarcoma* | Femur | 22 | M | 12.2 | 22.1 | 2.0 | 21.8 | Yes | 99 | 2 | Ewing’s Sarcoma* | Fibula | 19 | F | 4.7 | 7.8 | 1.7 | 7.8 | Yes | 90 | 3 | Osteosarcoma | Fibula | 23 | M | 3.6 | 6.8 | 2.3 | 6.5 | No | 90 | 4 | Osteosarcoma | Tibia | 58 | M | 9.7 | 8.5 | 2.9 | 8.8 | Yes | 90 | 5 | Ewing’s Sarcoma* | Femur | 29 | M | 6.8 | 17.3 | 2.7 | 17.3 | Yes | 80 | 6 | Osteosarcoma | Femur | 31 | F | 10.8 | 15.0 | 6.7 | 15.3 | No | 70 | 7 | Osteosarcoma | Tibia | 18 | F | 3.9 | 11.2 | 2.4 | 11.9 | No | 70 | 8 | Giant Cell Tumor* | Iliac Wing | 44 | F | 6.4 | 9.3 | 4.0 | 10.5 | No | 50 | 9 | Osteosarcoma | Femur | 32 | F | 5.0 | 6.5 | 4.8 | 6.8 | No | 30 | 10 | Chondrosarcoma* | Humerus | 61 | M | 15.7 | 17.4 | 10.6 | # | No | 30 | 11 | Chondrosarcoma | Sternum | 19 | F | 13.5 | 10.9 | 6.3 | 9.5 | No | 20 | 12 | Osteosarcoma | Tibia | 23 | F | 5.3 | 7.1 | 7.0 | 8.2 | No | 10 |
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*Patients received additional radiation therapy; # not measurable due to obliquity of bone.
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