Targeting the Insulin-Like Growth Factor Pathway in Rhabdomyosarcomas: Rationale and Future Perspectives

Figure 2

Levels of RNA expression for IGF2 derived from expression profiling data (Affymetrix HGU133plus2) in a panel of different tissues samples. These include normal skeletal muscle (Skeletal muscle), mesenchymal stem cells (MSC), ERMS, ARMS (PAX3-FOXO1 and PAX7-FOXO1 fusion positive, ARMS_P3F and ARMS_P7F and fusion gene negative ARMS_NEG) cases [13] and RMS cell lines (RH3, SCMC, RMS, RH30, RD, RMS-YM, RH18, Ruch3, T91-95, RH41, TE617T, Hs729T, T174, TE441T, Ruch2, and RH4) [30].