Research Article
Delineation of Chondroid Lipoma: An Immunohistochemical and Molecular Biological Analysis
Table 2
Immunohistochemical and fluorescence in situ hybridization results.
| | Histology | IHC | IHC | IHC | IHC | IHC | IHC | IHC | IHC | FISH | FISH | | CCND1 (%) | CD34 | CD68 | S100 | keratin | P63 | SMA | vimentin | Split apart CCND1 | Split apart FUS |
| | Chondroid lipoma () | | | | | | | | | | | | Positive | 4 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 0 | | Focal positive | 0 | 0 | 1 | 2 | 2 | 0 | 0 | 0 | n.a. | n.a. | | Negative | 0 | 4 | 3 | 1 | 2 | 4 | 4 | 1 | 4/4* | 4/4* |
| | Myoepithelioma () | | | | | | | | | | | | Positive | 1 | 0 | 0 | 3 | 3 | 0 | 0 | 4 | 0 | 0 | | Focal positive | 1 | 0 | 1 | 1 | 1 | 1 | 0 | 0 | n.a. | n.a. | | Negative | 2 | 4 | 3 | 0 | 0 | 3 | 4 | 0 | 4/4* | 3/3* |
| | Lipoma () | | | | | | | | | | | | Positive | 0 | — | — | — | — | — | — | — | — | — | | Focal positive | 16 (76) | — | — | — | — | — | — | — | — | — | | Negative | 5 (24) | — | — | — | — | — | — | — | — | — |
| | Well differentiated liposarcoma () | | | | | | | | | | | | Positive | 1 (4) | — | — | — | — | — | — | — | — | — | | Focal positive | 16 (57) | — | — | — | — | — | — | — | — | — | | Negative | 11 (39) | — | — | — | — | — | — | — | — | — |
| | Myxoid liposarcoma () | | | | | | | | | | | | Positive | 0 | — | — | — | — | — | — | — | — | — | | Focal positive | 0 | — | — | — | — | — | — | — | — | — | | Negative | 18 (100) | — | — | — | — | — | — | — | — | — |
| | Chondrosarcoma () | | | | | | | | | | | | Positive | 3 (30) | — | — | — | — | — | — | — | — | — | | Focal positive | 3 (30) | — | — | — | — | — | — | — | — | — | | Negative | 4 (40) | — | — | — | — | — | — | — | — | — |
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*There were no translocations observed.
n.a.: not applicable.
IHC: immunohistochemical.
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