Review Article
Targeted Therapy of Ewing's Sarcoma
Table 3
Uncommon (<10%) Grade 3 and 4 toxicities of antiinsulin-like growth factor 1 receptor (IGF1R) antibodies.
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DVT: deep venous thrombosis; PE: pulmonary embolism; CVA: cerebrovascular accident; LFT: liver function test; mTOR: mammalian target of rapamycin; GI: gastrointestinal. Note: Grade 3 or 4 toxicities have been seen in <10% of patients. These antibodies have generally been very well tolerated with few side effects compared to standard EWS chemotherapy. |