|
| RNase A sensitive | |
|
| hnRNP A0 [12] | Pre-mRNA processing, RNA metabolism, RNA transport |
| hnRNP A1 [12] | Pre-mRNA processing, RNA metabolism, and RNA transport may modulate splice site selection |
| hnRNP A2B1 [12] | Pre-mRNA processing, RNA metabolism, RNA transport |
| hnRNP A3 [12] | Regulation of age-related gene expression, binds to telomeric RNA |
| hnRNP A/B [12] | Binds to multiprotein editosome complex |
| hnRNP A18* [12] | Stabilization of transcripts, genotoxic stress response, translational activator, binds to 3′UTR |
| hnRNP D0 [12] | Regulation of mRNA stability |
| hnRNP F [12] | Binds G-rich sequences |
| hnRNP G [12] | Regulation of splice site selection, DNA double-strand break repair |
| hnRNP H [12] | Pre-mRNA alternative splicing regulation |
| hnRNP H2 [12] | Involved in Fabray disease and X-linked agammaglobulinemia |
| hnRNP H3 [12] | Early heat shock-induced splicing arrest |
| hnRNP Q [12] | RNA stability, translationally coupled mRNA turnover |
| Small nuclear ribonucleoprotein Sm D3 [12] | Pre-mRNA splicing and small nuclear ribonucleoprotein biogenesis, histone 3′-end processing |
| U1 small nuclear ribonucleoprotein A* [12] | First snRNP to interact with pre-mRNA for the subsequent binding of U2 snRNP and the U4/U6/U5 tri-snRNP |
| Splicing factor, arginine/serine-rich 1* [12, 44] | Accuracy of splicing and regulation of alternative splicing |
| Splicing factor, arginine/serine-rich 3* [12] | Putative proliferation-/maturation-associated RNA processing |
| Splicing factor, arginine/serine-rich 9* [12] | Constitutive splicing |
| RRM containing coactivator activator [12] | Activation/modulation of nuclear receptors |
| Tubulin alpha ubiquitous chain [12] | Scaffold for cell shape and organelle movement |
| Vimentin1 | Organizer of a number of critical proteins involved in attachment, migration, and cell signaling |
|
| RNase insensitive | |
|
| Protein arginine N methyltransferase 1 [12] | Epigenetic regulation, signal transduction, DNA repair |
| Protein arginine N-methyltransferase 8 [63] | Localized at cell membrane |
| hnRNP M [12] | Splicing, selective recycling of immature GlcNAc-bearing, thyroglobulin molecules, potentially involved in signalling |
| hnRNP U [12, 43] | Binds double- and single-stranded RNA and DNA, binds pre-mRNA |
| FUS** [12] | This review |
| TAF15* [12] | This review |
| EWS* [64] | This review |
| RNA-dependent helicase p68 (DDX5) [12] | RNA-dependent ATPase, alteration of RNA secondary structure in splicing and translation initiation |
| RNA-dependent helicase p72 (DDX17) [12] | RNA-dependent ATPase, alteration of RNA secondary structure in splicing, and translation initiation |
| ATP-dependent RNA helicase A [12] | ATP-dependent unwinding of double-stranded RNA and DNA-RNA complexes, transcriptional regulation |
| ATP-dependent RNA helicase DHX36* [12] | Deadenylation and decay of mRNAs with 3′-UTR AU-rich elements |
| Elongation factor EF1 gamma [12] | Translation elongation, role in anchoring the translational complex to other cellular components |
| Elongation factor EF1 alpha [12] | Translation elongation, promotes aminoacyl-tRNA binding to ribosome |
| Dead box protein 3 X (DDX3X)* [12] | ATP-dependent RNA helicase |
| Tubuline beta-2 chain [12] | Scaffold for cell shape and organelle movement |
|
| RNA dependence unknown: | |
|
| RBP3 [29] | RNA Polymerase II component |
| TAF5 [29] | General transcription factor TFIID component |
| TAF7 [29] | General transcription factor TFIID component |
| TAF11 [29] | General transcription factor TFIID component |
| TAF13 [29] | General transcription factor TFIID component |
| Brn-3a [35] | Transcription factor |
| SF1 [47] | Splicing factor |
| YB1 [42] | Splicing factor |
| Survival motor neuron protein* [65] | Essential role in spliceosomal snRNP assembly in the cytoplasm and is required for pre-mRNA splicing in the nucleus |
| Serine threonine kinase receptor (STRAP) [33] | Inhibits transforming growth factor beta (TGF-beta) signaling |
| BARD1 [53] | DNA repair, mRNA maturation |
| Pyk2 [66] | Tyrosine kinase, signal transduction |
|
