Review Article

Proteomic Technologies for the Study of Osteosarcoma

Figure 1

MRI and histological appearance of osteosarcoma. (a) Coronal view MRI reveals diffuse involvement of the distal femur with elevation of the periosteum (small arrow) and diffuse intramedullary involvement (large arrow). (b) Axial view of an MRI reveals elevation of the periosteum due to malignant cells. (c) The classic histological appearance of osteosarcoma. Lace-like pattern osteoid production (small arrow) and malignant cells (large arrow). (d) Higher magnification of (c) to better appreciate the malignant cells.
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