Proteomic Technologies for the Study of Osteosarcoma

Table 1

Commonly identified proteins from multiple proteomic studies. The first column represents the accession number of the protein, followed by the protein name. The last column contains the author’s last name and year of the publication the protein was found to be significantly differentiated with the expression level indicated in parentheses.

Accession	Protein name	References (regulation)
GI: 5453832	150 kDa oxygen-regulated protein (precursor)	Zhang et al. 2009 [52] (down); Spreafico et al. 2006 [53] (up); Niforou et al. 2008 [25]
P08865	40S ribosomal protein SA	Folio et al. 2009 [54] (down); Kang et al. 2006 [55] (down)
P49189	4-Trimethylaminobutyraldehyde dehydrogenase	Guo et al. 2007 [8] (down); Niforou et al. 2008 [25]
P05388	60S acidic ribosomal protein P0	Guo et al. 2007 [8] (up); Kang et al. 2006 [55] (down)
GI: 4916999	78 kDa glucose-regulated protein	Zhang et al. 2009 [52] (down); Niforou et al. 2008 [25]
P60709	Actin, cytoplasmic 1	Hua et al. 2011 [60] (down); Niforou et al. 2008 [25]
P63261	Actin cytoplasmic 2	Folio et al. 2009 [54] (down); Zhang et al. 2010 [56] (down); Niforou et al. 2008 [25]
O95433	Activator of 90 kDa heat shock protein ATPase homolog 1	Guo et al. 2007 [8] (up); Niforou et al. 2008 [25]
P30837	Aldehyde dehydrogenase X, mitochondrial (precursor)	Kang et al. 2006 [55] (up); Niforou et al. 2008 [25]
GI: 127801853	Alkaline phosphatase, liver/bone/kidney	Spreafico et al. 2006 [53] (up); Zhang et al. 2009 [52] (up)
P06733	Alpha enolase	Li et al. 2006 [27] (up); Folio et al. 2009 [54] (down)
P04083	Annexin A1	Cates et al. 2010 [26] (up); Spreafico et al. 2006 [53] (down); Kang et al. 2006 [55] (up); Niforou et al. 2008 [25]
P07355	Annexin A2	Spreafico et al. 2006 [53] (down); Zhang et al. 2010 [56] (up); Niforou et al. 2008 [25]
P08758	Annexin A5	Liu et al. 2009 [57] (down); Niforou et al. 2008 [25]
O95816	BAG-family molecular chaperone	Chang et al. 2008 [58] (down); Niforou et al. 2008 [25]
Q15417	Calponin-3	Guo et al. 2007 [8] (up); Niforou et al. 2008 [25]
P27797	Calreticulin (precursor)	Hua et al. 2011 [60] (up); Zhang et al. 2009 [52] (up); Niforou et al. 2008 [25]
P07339	Cathepsin D precursor	Spreafico et al. 2006 [53] (down); Li et al. 2006 [27] (down)
P12277	Creatine kinase B-type	Spreafico et al. 2006 [53] (up); Niforou et al. 2008 [25]
P06730	Eukaryotic translation initiation factor 4E	Kang et al. 2006 [55] (down); Niforou et al. 2008 [25]
P15311	Ezrin	Li et al. 2010 [28] (up); Folio et al. 2009 [54] (up); Guo et al. 2007 [8] (down)
P52907	F-actin capping protein subunit alpha-1	Kang et al. 2006 [55] (down); Niforou et al. 2008 [25]
P02792	Ferritin light chain	Li et al. 2010 [28] (up); Niforou et al. 2008 [25]
Q02790	FK506-binding protein 4	Guo et al. 2007 [8] (up); Niforou et al. 2008 [25]
P04075	Fructose-bisphosphate aldolase A	Kang et al. 2006 [55] (up); Niforou et al. 2008 [25]
P09972	Fructose-bisphosphate aldolase C	Chang et al. 2008 [58] (up); Kang et al. 2006 [55] (up); Niforou et al. 2008 [25]
P09382	Galectin-1	Zhang et al. 2010 [56] (up); Spreafico et al. 2006 [53] (down); Niforou et al. 2008 [25]
P11142	Heat-shock cognate 71 kDa protein	Li et al. 2006 [27] (up); Niforou et al. 2008 [25]
Q5IST7	Heat-shock 70	Zhao et al. 2010 [59] (down); Liu et al. 2009 [57] (up)
P11142	Heat-shock cognate 71 kDa protein	Li et al. 2006 [27] (up); Niforou et al. 2008 [25]
P31943	Heterogeneous nuclear ribonucleoprotein H	Kang et al. 2006 [55] (up); Li et al. 2006 [27] (up); Niforou et al. 2008 [25]
P61 978	Heterogeneous nuclear ribonucleoprotein K	Li et al. 2006 [27] (down); Niforou et al. 2008 [25]
P14866	Heterogeneous nuclear ribonucleoprotein L	Chang et al. 2008 [58] (up); Kang et al. 2006 [55] (up); Niforou et al. 2008 [25]
Q15181	Inorganic pyrophosphatase	Kang et al. 2006 [55] (down); Niforou et al. 2008 [25]
Q03252	Lamin-B2	Li et al. 2010 [28] (up); Niforou et al. 2008 [25]
P07195	L-Lactate dehydrogenase B chain	Spreafico et al. 2006 [53] (up); Niforou et al. 2008 [25]
P43243	Matrin-3	Li et al. 2006 [27] (down); Niforou et al. 2008 [25]
P19338	Nucleolin	Li et al. 2006 [27] (down); Niforou et al. 2008 [25]
P06748	Nucleophosmin	Zhao et al. 2010 [59] (down); Folio et al. 2009 [54] (down); Niforou et al. 2008 [25]
P35232	Prohibitin	Zhao et al. 2010 [59] (down); Cates et al. 2010 [26] (up); Kang et al. 2006 [55] (down); Niforou et al. 2008 [25]
P25786	Proteasome subunit alpha type 1	Zhang et al. 2009 [52] (down); Li et al. 2006 [27] (down); Niforou et al. 2008 [25]
P14618	Pyruvate kinase isozymes M1/M2	Folio et al. 2009 [54] (down); Guo et al. 2007 [8] (up); Niforou et al. 2008 [25]
Q15459	Splicing factor 3 subunit 1	Chang et al. 2008 [58] (up); Niforou et al. 2008 [25]
P20152	Vimentin	Cates et al. 2010 [57] (up); Li et al. 2010 [28] (up); Zhang et al. 2010 [56] (up); Zhao et al. 2010 [59] (down); Zhang et al. 2009 [52] (down); Kang et al. 2006 [55] (down); Li et al. 2006 [27] (up); Zhao et al. 2006 [86] (up); Niforou et al. 2008 [25]