Review Article

Downstream and Intermediate Interactions of Synovial Sarcoma-Associated Fusion Oncoproteins and Their Implication for Targeted Therapy

Figure 1

Schematic diagram shows the domains structure of SS18 and SSX proteins. The amino acid residues representing the boundaries of selected domains are indicated. SNH-SS18 N-terminal domain; QPGY-SS18 domain rich in glutamine, proline, glycine, and tyrosine; KRAB-SSX Krüppel-associated box domain; SSXRD-SSX transcriptional repression domain.
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