Research Article

rAAV Vectors as Safe and Efficient Tools for the Stable Delivery of Genes to Primary Human Chondrosarcoma Cells In Vitro and In Situ

Figure 4

Effects of rAAV-mediated gene transfer on the survival of transduced primary human chondrosarcoma in situ. Human chondrosarcoma explant cultures were transduced with rAAV-lacZ (40 μL) or let untreated and processed after 20 days for H&E staining (a), immunodetection of Ki-67 (b), and TUNEL assay (c). All at magnification ×20 except for H&E staining (magnification ×10).
347417.fig.004a
(a)
347417.fig.004b
(b)
347417.fig.004c
(c)