Table 3: Summay of protein expression studies using patient’s tissue samples of osteosarcoma.
(a)

Protein nameFolio et al. (osteosarcoma versus normal bone)Li et al. (osteosarcoma versus benign bone tumor)Kikuta et al. (poor responder versus good responder)

40S ribosomal protein SAFolio_4 (OS )Kikuta_27 (poor )
Alpha-actinin-1Kikuta_10 (poor )
Alpha-enolaseKikuta_20, Kikuta_21 (poor )
Alpha1-antitrypsinLi_11 (OS )
Actin cytoplasmic 2Folio_16 (OS )
Actin-betaLi_14 (OS )
Actin-gamma1 Li_4 (OS )
Adenylate cyclase 1Li_13 (OS )
Alpha crystallin beta chainFolio_13 (OS )
Alpha-enolase Folio_8 (OS )
Annexin A6Kikuta_1 (poor )
ATP synthase mitochondrial F1 complex b polypeptideLi_16 (OS )
ATP synthase subunit bKikuta_39 (poor )
C-type lectin domain family 11 member AKikuta_4 (poor )
Carbonic anhydrase 1Kikuta_52, Kikuta_54 (poor )
Chaperonin containing TCP1 Li_12 (OS )
Clusterin precursorKikuta_2 (poor )
CNDP dipeptidase 2Kikuta_17 (poor )
Coatomer protein complex Li_3 (OS )
Collagen alpha-1Kikuta_55 (poor )
Desmoglein-1Kikuta_46 (poor )
Elongation factor 1-gammaKikuta_34 (poor )
Eukaryotic initiation factor 4A-IKikuta_38 (poor )
EzrinFolio_7 (OS )Li_9 (OS )
FascinFolio_12 (OS )
Ferritin light polypeptideLi_7 (OS )
Haptoglobin-related proteinKikuta_31, Kikuta_53 (poor )
Heat shock 70 kDa protein 1Kikuta_19 (poor )
Heat shock cognate 71 kDa proteinFolio_6 (OS )Kikuta_23, Kikuta_25 (poor )
Heat shock protein beta 6Folio_1 (OS )
Heme binding protein 1Folio_2 (OS )
Hemoglobin subunit betaKikuta_7, 11, 15, 28, 36 (poor )
Keratin type II cytoskeletal 1Kikuta_9 (poor )
Lamin B2Li_1 (OS )
Lamin-A/CKikuta_29 (poor )
LIM and SH3 domain protein 1 Folio_9 (OS )
LumicanKikuta_43 (poor )
Myosin light chain 6 alkali smooth muscle and nonmuscleLi_8 (OS )
NADH-ubiquinone oxidoreductaseKikuta_22 (poor )
Nucleophosmin Folio_5 (OS )
Peroxiredoxin 6Folio_11 (OS )
Peroxiredoxin 2Kikuta_30 (poor )
PR65-A isoformKikuta_50 (poor )
Proteasome activator complex subunit 1Kikuta_16 (poor )
Purine nucleoside phosphorylaseKikuta_12 (poor )
Pyruvate kinase isozymes M1/M2Folio_14 (OS )
Reticulocalbin 3 Li_17 (OS )Kikuta_13 (poor )
Ribose-phosphate pyrophosphokinase IIKikuta_35 (poor )
Septin-11Folio_15 (OS )
Serum albuminKikuta_14, 41, 48 (poor )
Stress-70 proteinKikuta_3, 24 (poor )
Thioredoxin reductase 1Folio_10 (OS )
TransferrinLi_10 (OS )
Trypsin-3 precursorKikuta_8, 26, 32 (poor↑ )
Tubulin alpha-ubiquitous chainKikuta_45 (poor )
Tubulin beta-2A chainKikuta_47 (poor )
Tubulin beta-2C chainKikuta_37 (poor )
Tubulin beta-chainKikuta_44 (poor )
Tubulin-alpha-1CLi_6 (OS )
Tubulin-betaLi_15 (OS )
Tumor protein D54Kikuta_40, 49 (poor )
Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein Li_18 (OS )
Ubiquitin carboxyl terminal hydrolase isozyme L1Folio_3 (OS )
UV excision repair protein RAD23Kikuta_33, 51 (poor )
Vesicle-fusing ATPaseKikuta_42 (poor )
VimentinLi_2 (OS )Kikuta_5, 6, 18 (poor )
Zinc finger protein 133Li_5 (OS )

(b)

Protein nameFolio et al. (OS versus normal bone)Li et al. (OS versus benign tumor)Kikuta et al. (poor responder versus good responder)

40S ribosomal protein SAFolio_4 (OS )Kikuta_27 (poor )
EzrinFolio_7 (OS )Li_9 (OS )
Heat shock cognate 71 kDa proteinFolio_6 (OS )Kikuta_25 (poor )
Reticulocalbin 3Li_17 (OS )Kikuta_13 (poor )
VimentinLi_2 (OS )Kikuta_5, _6, 18 (poor )
PRDX familyFolio_11 (PRDX6) (OS )Kikuta_30 (PRDX2) (poor )