Prognostic Value of Microvessel Density in Tumor and Peritumoral Area as Evaluated by CD31 Protein Expression and Argyrophilic Nucleolar Organizer Region Count in Endothelial Cells in Uterine Leiomyosarcoma

Table 2

The number of AgNORs of endothelial cells and the MVD in the PA and LMS of different stages and grades of malignancy.

Object of study		CD31	AgNORs of endothelial cells
PA (𝑛=66)		64.4 ± 4.4	1.85 ± 0.1^*
		(min—10; max—104)	(min—1; max—3)
Sarcoma of different grades of malignancy	G1	79.3 ± 8.5	8.3 ± 5.3^#
	(𝑛=30)	(min—9.0; max—201)	(min—3; max—13)
	G2	68.2 ± 16.6	9.8 ± 1.5
	(𝑛=17)	(min—8.6; max—268)	(min—2; max—14)
	G3	59.1 ± 9.1	16.7 ± 4.8^#
	(𝑛=19)	(min—13; max—148)	(min—5; max—62)
Sarcoma of different stages	I	80.7 ± 8.3	10.3 ± 1.5
	(𝑛=43)	(min—9; max—268)	(min—3; max—32)
	II	52.2 ± 8.7	13.5 ± 4.3
	(𝑛=23)	(min—8.6; max—148)	(min—5; max—62)

∗Differences in the number of AgNORs of endothelial cells in the PA and LMS at 𝑃≤0.05.
#Differences between groups of different grades of malignancy at 𝑃≤0.05.