About this Journal Submit a Manuscript Table of Contents
Sarcoma
Volume 2012 (2012), Article ID 620834, 12 pages
http://dx.doi.org/10.1155/2012/620834
Research Article

Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST

1Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA
2Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA
3Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA
4Brain Tumor Program, University of Minnesota, Minneapolis, MN 55455, USA
5Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong
6Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL 32610, USA
7Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Research Foundation, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA
8Division of Pathology and Laboratory Medicine, Cincinnati Children’s Hospital Research Foundation, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA
9UF Shands Cancer Center, Genetics Institute, University of Florida, Gainesville, FL 32610, USA
10Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA

Received 6 August 2012; Accepted 2 November 2012

Academic Editor: R. Pollock

Copyright © 2012 Vincent W. Keng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Citations to this Article [5 citations]

The following is the list of published articles that have cited the current article.

  • Branden S. Moriarity, Caitlin B. Conboy, Amanda L. Halfond, Leah K. Anderson, Brian R. Wahl, David A. Largaespada, Eric P. Rahrmann, Kwangmin Choi, Vincent W. Keng, Anthony E. Rizzardi, Stephen C. Schmechel, Andrew D. Greeley, Adrienne L. Watson, Colleen L. Forster, Margaret H. Collins, Aaron L. Sarver, Margaret R. Wallace, and Nancy Ratner, “Canonical Wnt/beta-catenin Signaling Drives Human Schwann Cell Transformation, Progression, and Tumor Maintenance,” Cancer Discovery, vol. 3, no. 6, pp. 674–689, 2013. View at Publisher · View at Google Scholar
  • Jinlong Ding, and Eric Delpire, “Deletion of KCC3 in parvalbumin neurons leads to locomotor deficit in a conditional mouse model of peripheral neuropathy associated with agenesis of the corpus callosum,” Behavioural Brain Research, 2014. View at Publisher · View at Google Scholar
  • Eric P. Rahrmann, Branden S. Moriarity, George M. Otto, Adrienne L. Watson, Kwangmin Choi, Margaret H. Collins, Margaret Wallace, Beau R. Webber, Colleen L. Forster, Anthony E. Rizzardi, Stephen C. Schmechel, Nancy Ratner, and David A. Largaespada, “Trp53 Haploinsufficiency Modifies EGFR-Driven Peripheral Nerve Sheath Tumorigenesis,” The American Journal of Pathology, 2014. View at Publisher · View at Google Scholar
  • Changxin Xu, Xiufen Li, Matthew K. Topham, and Scott K. Kuwada, “Regulation of sonic hedgehog expression by integrin β1 and epidermal growth factor receptor in intestinal epithelium,” IUBMB Life, 2014. View at Publisher · View at Google Scholar
  • Barbara R. Tschida, David A. Largaespada, and Vincent W. Keng, “Mouse Models of Cancer: Sleeping Beauty Transposons for Insertional Mutagenesis Screens and Reverse Genetic Studies,” Seminars in Cell & Developmental Biology, 2014. View at Publisher · View at Google Scholar