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Volume 2012 (2012), Article ID 620834, 12 pages
Conditional Inactivation of Pten with EGFR Overexpression in Schwann Cells Models Sporadic MPNST
1Masonic Cancer Center, University of Minnesota, Minneapolis, MN 55455, USA
2Department of Genetics, Cell Biology and Development, University of Minnesota, Minneapolis, MN 55455, USA
3Center for Genome Engineering, University of Minnesota, Minneapolis, MN 55455, USA
4Brain Tumor Program, University of Minnesota, Minneapolis, MN 55455, USA
5Department of Applied Biology and Chemical Technology, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong
6Department of Molecular Genetics and Microbiology, University of Florida, Gainesville, FL 32610, USA
7Division of Experimental Hematology and Cancer Biology, Cincinnati Children’s Hospital Research Foundation, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA
8Division of Pathology and Laboratory Medicine, Cincinnati Children’s Hospital Research Foundation, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH 45229, USA
9UF Shands Cancer Center, Genetics Institute, University of Florida, Gainesville, FL 32610, USA
10Department of Pediatrics, University of Minnesota, Minneapolis, MN 55455, USA
Received 6 August 2012; Accepted 2 November 2012
Academic Editor: R. Pollock
Copyright © 2012 Vincent W. Keng et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Citations to this Article [6 citations]
The following is the list of published articles that have cited the current article.
- Branden S. Moriarity, Caitlin B. Conboy, Amanda L. Halfond, Leah K. Anderson, Brian R. Wahl, David A. Largaespada, Eric P. Rahrmann, Kwangmin Choi, Vincent W. Keng, Anthony E. Rizzardi, Stephen C. Schmechel, Andrew D. Greeley, Adrienne L. Watson, Colleen L. Forster, Margaret H. Collins, Aaron L. Sarver, Margaret R. Wallace, and Nancy Ratner, “Canonical Wnt/beta-catenin Signaling Drives Human Schwann Cell Transformation, Progression, and Tumor Maintenance,” Cancer Discovery, vol. 3, no. 6, pp. 674–689, 2013.
- Jinlong Ding, and Eric Delpire, “Deletion of KCC3 in parvalbumin neurons leads to locomotor deficit in a conditional mouse model of peripheral neuropathy associated with agenesis of the corpus callosum,” Behavioural Brain Research, 2014.
- Eric P. Rahrmann, Branden S. Moriarity, George M. Otto, Adrienne L. Watson, Kwangmin Choi, Margaret H. Collins, Margaret Wallace, Beau R. Webber, Colleen L. Forster, Anthony E. Rizzardi, Stephen C. Schmechel, Nancy Ratner, and David A. Largaespada, “Trp53 Haploinsufficiency Modifies EGFR-Driven Peripheral Nerve Sheath Tumorigenesis,” The American Journal of Pathology, 2014.
- Changxin Xu, Xiufen Li, Matthew K. Topham, and Scott K. Kuwada, “Regulation of sonic hedgehog expression by integrin β1 and epidermal growth factor receptor in intestinal epithelium,” IUBMB Life, 2014.
- Barbara R. Tschida, David A. Largaespada, and Vincent W. Keng, “Mouse Models of Cancer: Sleeping Beauty Transposons for Insertional Mutagenesis Screens and Reverse Genetic Studies,” Seminars in Cell & Developmental Biology, 2014.
- Ellie Rad, Kayleigh Dodd, Laura Thomas, Meena Upadhyaya, and Andrew Tee, “STAT3 and HIF1 alpha Signaling Drives Oncogenic Cellular Phenotypes in Malignant Peripheral Nerve Sheath Tumors,” Molecular Cancer Research, vol. 13, no. 7, pp. 1149–1160, 2015.