Review Article

Solitary Fibrous Tumors and So-Called Hemangiopericytoma

Table 2

Characteristics of the paediatric cases reported in the literature.

Ref.LocationAgeSize macroscopic aspectHistology and immunohistochemistryOutcome

[12]Mesentery6 y.o.10 × 8 × 7 cm
Well-defined solid mass
Encapsulated tumor
Solid and cystic parts
Uniform hypercellular areas of pleomorphic spindle cells intermixed with a dense collagenous stroma with few necrotic areas.
25 mitoses per 50 HPF
  (i) CD34 positive
  (ii) NSE positive
  (iii) DOG-1, Bcl-2, CD117, desmin, S-100 protein, and SMA negative.
No lymph node metastasis was present at diagnosis.
Liver metastasis after 8 months

[13]Pleura7 y.o.5 × 5 × 4 cm
Well-demarcated nodular mass
Low cellularity
  (i) CD34, vimentin and bcl2, positive
  (ii) Cytokeratin, SMA, desmin, and S100 negative
No metastasis.
No evidence of tumor recurrence 9 months later

[14]Orbit15 y.o.1.5 × 1.4 × 1.0 cm
Well-circumscribed mass
Highly vascular
Highly cellular spindle tumor
2 mitoses per 20 HPF
  (i) AE1/AE2 cytokeratin, smooth-muscle actin, muscle-specific actin, desmine, S100 negative
  (ii) CD34. and vimentin positive
No metastasis
No recurrence after local radiotherapy