Comparative Gene Expression Profiling of Benign and Malignant Lesions Reveals Candidate Therapeutic Compounds for Leiomyosarcoma
Figure 4
In vitro cell viability assays of 11 drugs on three LMS cell lines. Three LMS cell lines, LMS03, LMS04, and LMS05, were exposed to the indicated drugs at concentrations ranging from 0 to10 M. Cell viability was assessed 72 h after exposure to drugs using WST-1 assays and experiments were performed in triplicate. Data are arranged in order of decreasing magnitude of cmap enrichment scores for LMS Subtype II, which all three cell lines most closely resembled according to our analysis.
