Putative Multifunctional Signature of Lung Metastases in Dedifferentiated Chondrosarcoma

Table 2

“Biased multifunctional signature” of dedifferentiated chondrosarcoma lung metastases.

Upregulated in Met.-cell lines
Gene name	Gene symbol
Plasminogen activator, Tissue	PLAT*
Plasminogen activator, Urokinase	PLAU*
Interleukin 8	IL8*
Chemokine (C-C motif) ligand 2	CCL2
Integrin, beta 1	ITGB1
Actin, beta	ACTB
Vinculin	VCL
Drebrin 1	DBN1*
Moesin	MSN*
Tissue factor pathway inhibitor 2	TFPI2*
Caveolin 1	CAV1
Caveolin 2	CAV2*
Tenascin-C	TNC*
Downregulated in Met.-cell lines
Transforming growth factor, beta-induced, 68 kDA	TGFBI
Serpin peptidase inhibitor, clade E, member 2	SERPINE2

*Genes uniquely expressed in the metastases.