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Sarcoma
Volume 2013 (2013), Article ID 160295, 8 pages
http://dx.doi.org/10.1155/2013/160295
Clinical Study

Intercalary Reconstructions with Vascularised Fibula and Allograft after Tumour Resection in the Lower Limb

Department of Orthopaedic Surgery, Medical University of Graz, Auenbruggerplatz 5, 8036 Graz, Austria

Received 3 February 2013; Revised 9 April 2013; Accepted 28 April 2013

Academic Editor: Per-Ulf Tunn

Copyright © 2013 Katharina Rabitsch et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. W. W. Huh, C. Yuen, M. Munsell, A. Hayes-Jordan, A. J. Lazar, et al., “Liposarcoma in children and young adults: a multi-institutional experience,” Pediatric Blood & Cancer, vol. 57, pp. 1142–1146, 2011. View at Publisher · View at Google Scholar
  2. E. J. Stanelle, E. R. Christison-Lagay, E. L. Sidebotham et al., “Prognostic factors and survival in pediatric and adolescent liposarcoma,” Sarcoma, vol. 2012, Article ID 870910, 6 pages, 2012. View at Publisher · View at Google Scholar
  3. P. X. Tan, B. C. Yong, J. Wang et al., “Analysis of the efficacy and prognosis of limb-salvage surgery for osteosarcoma around the knee,” European Journal of Surgical Oncology, vol. 38, pp. 1171–1177, 2012. View at Publisher · View at Google Scholar
  4. G. Bacci, A. Briccoli, S. Ferrari et al., “Neoadjuvant chemotherapy for osteosarcoma of the extremity: long-term results of the Rizzoli's 4th protocol,” European Journal of Cancer, vol. 37, no. 16, pp. 2030–2039, 2001. View at Publisher · View at Google Scholar · View at Scopus
  5. E. Arpaci, T. Yetisyigit, M. Seker, D. Uncu, U. Uyeturk, et al., “Prognostic factors and clinical outcome of patients with Ewing's sarcoma family of tumors in adults: multicentric study of the anatolian society of medical oncology,” Medical Oncology, vol. 30, p. 469, 2013. View at Publisher · View at Google Scholar
  6. M. J. Krasin, A. M. Davidoff, C. Rodriguez-Galindo et al., “Definitive surgery and multiagent systemic therapy for patients with localized ewing sarcoma family of tumors: local outcome and prognostic factors,” Cancer, vol. 104, no. 2, pp. 367–373, 2005. View at Publisher · View at Google Scholar · View at Scopus
  7. M. A. Simon, M. A. Aschliman, N. Thomas, and H. J. Mankin, “Limb-salvage treatment versus amputation for osteosarcoma of the distal end of the femur: commentary,” Journal of Bone and Joint Surgery A, vol. 87, no. 12, p. 2822, 2005. View at Publisher · View at Google Scholar · View at Scopus
  8. D. L. Muscolo, M. A. Ayerza, L. A. Aponte-Tinao, and M. Ranalletta, “Partial epiphyseal preservation and intercalary allograft reconstruction in high-grade metaphyseal osteosarcoma of the knee,” Journal of Bone and Joint Surgery A, vol. 86, no. 12, pp. 2686–2693, 2004. View at Scopus
  9. B. Fuchs, C. Ossendorf, T. Leerapun, and F. H. Sim, “Intercalary segmental reconstruction after bone tumor resection,” European Journal of Surgical Oncology, vol. 34, no. 12, pp. 1271–1276, 2008. View at Publisher · View at Google Scholar · View at Scopus
  10. R. C. Thompson, A. Garg, D. R. Clohisy, and E. Y. Cheng, “Fractures in large segment allografts,” Clinical Orthopaedics and Related Research, no. 370, pp. 227–235, 2000. View at Scopus
  11. M. San-Julian and J. Cañadell, “Fractures of allografts used in limb preserving operations,” International Orthopaedics, vol. 22, no. 1, pp. 32–36, 1998. View at Publisher · View at Google Scholar · View at Scopus
  12. M. San Julian Aranguren, M. Leyes, G. Mora, and J. Canadell, “Consolidation of massive bone allografts in limb-preserving operations for bone tumours,” International Orthopaedics, vol. 19, no. 6, pp. 377–382, 1995. View at Scopus
  13. M. Ceruso, F. Taddei, P. Bigazzi, and M. Manfrini, “Vascularised fibula graft inlaid in a massive bone allograft: considerations on the bio-mechanical behaviour of the combined graft in segmental bone reconstructions after sarcoma resection,” Injury, vol. 39, supplement 3, pp. S68–S74, 2008. View at Scopus
  14. T. H. Chen, W. M. Chen, and C. K. Huang, “Reconstruction after intercalary resection of malignant bone tumours. Comparison between segmental allograft and extracorporeally-irradiated autograft,” Journal of Bone and Joint Surgery B, vol. 87, no. 5, pp. 704–709, 2005. View at Publisher · View at Google Scholar · View at Scopus
  15. M. N. Zimel, A. M. Cizik, T. B. Rapp, J. S. Weisstein, and E. U. Conrad, “Megaprosthesis versus condyle-sparing intercalary allograft: distal femoral sarcoma,” Clinical Orthopaedics and Related Research, vol. 467, no. 11, pp. 2813–2824, 2009. View at Publisher · View at Google Scholar · View at Scopus
  16. D. L. Muscolo, M. A. Ayerza, L. Aponte-Tinao, M. Ranalletta, and E. Abalo, “Intercalary femur and tibia segmental allografts provide an acceptable alternative in reconstructing tumor resections,” Clinical Orthopaedics and Related Research, no. 426, pp. 97–102, 2004. View at Publisher · View at Google Scholar · View at Scopus
  17. E. Ortiz-Cruz, M. C. Gebhardt, L. C. Jennings, D. S. Springfield, and H. J. Mankin, “The results of transplantation of intercalary allografts after resection of tumors. A long-term follow-up study,” Journal of Bone and Joint Surgery A, vol. 79, no. 1, pp. 97–106, 1997. View at Scopus
  18. R. L. M. Deijkers, R. M. Bloem, H. M. Kroon, J. B. Van Lent, R. Brand, and A. H. M. Taminiau, “Epidiaphyseal versus other intercalary allografts for tumors of the lower limb,” Clinical Orthopaedics and Related Research, no. 439, pp. 151–160, 2005. View at Publisher · View at Google Scholar · View at Scopus
  19. B. J. Miller and W. W. Virkus, “Intercalary allograft reconstructions using a compressible intramedullary nail: a preliminary report,” Clinical Orthopaedics and Related Research, vol. 468, no. 9, pp. 2507–2513, 2010. View at Publisher · View at Google Scholar · View at Scopus
  20. L. E. Ramseier, T. I. Malinin, H. T. Temple, W. A. Mnaymneh, and G. U. Exner, “Allograft reconstruction for bone sarcoma of the tibia in the growing child,” Journal of Bone and Joint Surgery B, vol. 88, no. 1, pp. 95–99, 2006. View at Publisher · View at Google Scholar · View at Scopus
  21. C. H. Gerrand, A. M. Griffin, A. M. Davis, A. E. Gross, R. S. Bell, and J. S. Wunder, “Large segment allograft survival is improved with intramedullary cement,” Journal of Surgical Oncology, vol. 84, no. 4, pp. 198–208, 2003. View at Publisher · View at Google Scholar · View at Scopus
  22. B. A. Alman, A. De Bari, and J. I. Krajbich, “Massive allografts in the treatment of osteosarcoma and Ewing sarcoma in children and adolescents,” Journal of Bone and Joint Surgery A, vol. 77, no. 1, pp. 54–64, 1995. View at Scopus
  23. J. A. Cara, A. Lacleriga, and J. Canadell, “Intercalary bone allografts: 23 tumor cases followed for 3 years,” Acta Orthopaedica Scandinavica, vol. 65, no. 1, pp. 42–46, 1994. View at Scopus
  24. R. Pollock, P. Stalley, K. Lee, and D. Pennington, “Free vascularized fibula grafts in limb-salvage surgery,” Journal of Reconstructive Microsurgery, vol. 21, no. 2, pp. 79–84, 2005. View at Publisher · View at Google Scholar · View at Scopus
  25. R. W. W. Hsu, M. B. Wood, F. H. Sim, and E. Y. S. Chao, “Free vascularised fibular grafting for reconstruction after tumour resection,” Journal of Bone and Joint Surgery B, vol. 79, no. 1, pp. 36–42, 1997. View at Publisher · View at Google Scholar · View at Scopus
  26. A. Zaretski, A. Amir, I. Meller et al., “Free fibula long bone reconstruction in orthopedic oncology: a surgical algorithm for reconstructive options,” Plastic and Reconstructive Surgery, vol. 113, no. 7, pp. 1989–2000, 2004. View at Publisher · View at Google Scholar · View at Scopus
  27. T. A. El-Gammal, A. El-Sayed, and M. M. Kotb, “Microsurgical reconstruction of lower limb bone defects following tumor resection using vascularized fibula osteoseptocutaneous flap,” Microsurgery, vol. 22, no. 5, pp. 193–198, 2002. View at Publisher · View at Google Scholar · View at Scopus
  28. S. M. Amr, A. O. El-Mofty, S. N. Amin, A. M. Morsy, O. M. El-Malt, and H. A. Abdel-Aal, “Reconstruction after resection of tumors around the knee: role of the free vascularized fibular graft,” Microsurgery, vol. 20, pp. 233–251, 2000.
  29. Y. F. Yang, G. M. Zhang, Z. H. Xu, and J. W. Wang, “Homeochronous usage of structural bone allografts with vascularized fibular autografts for biological repair of massive bone defects in the lower extremities after bone tumor excision,” Journal of Reconstructive Microsurgery, vol. 26, no. 2, pp. 109–115, 2010. View at Publisher · View at Google Scholar · View at Scopus
  30. R. Capanna, D. A. Campanacci, N. Belot et al., “A new reconstructive technique for intercalary defects of long bones: the association of massive allograft with vascularized fibular autograft. long-term results and comparison with alternative techniques,” Orthopedic Clinics of North America, vol. 38, no. 1, pp. 51–60, 2007. View at Publisher · View at Google Scholar · View at Scopus
  31. J. Li, Z. Wang, Z. Guo, G. J. Chen, S. W. Li, and G. X. Pei, “The use of massive allograft with intramedullary fibular graft for intercalary reconstruction after resection of tibial malignancy,” Journal of Reconstructive Microsurgery, vol. 27, no. 1, pp. 37–45, 2011. View at Publisher · View at Google Scholar · View at Scopus
  32. J. Li, Z. Wang, Z. Guo, G. J. Chen, J. Fu, and G. X. Pei, “The use of allograft shell with intramedullary vascularized fibula graft for intercalary reconstruction after diaphyseal resection for lower extremity bony malignancy,” Journal of Surgical Oncology, vol. 102, no. 5, pp. 368–374, 2010. View at Publisher · View at Google Scholar · View at Scopus
  33. T. Jager, P. Journeau, G. Dautel, S. Barbary, T. Haumont, and P. Lascombes, “Is combining massive bone allograft with free vascularized fibular flap the children's reconstruction answer to lower limb defects following bone tumour resection?” Orthopaedics and Traumatology, vol. 96, no. 4, pp. 340–347, 2010. View at Publisher · View at Google Scholar · View at Scopus
  34. M. Innocenti, Y. Y. Abed, G. Beltrami, L. Delcroix, M. Manfrini, and R. Capanna, “Biological reconstruction after resection of bone tumors of the proximal tibia using allograft shell and intramedullary free vascularized fibular graft: lsong-term results,” Microsurgery, vol. 29, no. 5, pp. 361–372, 2009. View at Publisher · View at Google Scholar · View at Scopus
  35. Y. Y. Abed, G. Beltrami, D. A. Campanacci, M. Innocenti, G. Scoccianti, and R. Capanna, “Biological reconstruction after resection of bone tumours around the knee: long-term follow-up,” Journal of Bone and Joint Surgery B, vol. 91, no. 10, pp. 1366–1372, 2009. View at Publisher · View at Google Scholar · View at Scopus
  36. S. L. Moran, A. Y. Shin, and A. T. Bishop, “The use of massive bone allograft with intramedullary free fibular flap for limb salvage in a pediatric and adolescent population,” Plastic and Reconstructive Surgery, vol. 118, no. 2, pp. 413–419, 2006. View at Publisher · View at Google Scholar · View at Scopus
  37. L. Bernd, D. Sabo, A. Zahlten-Hinguranage, P. Niemeyer, W. Daecke, and H. G. Simank, “Experience with a vascularized fibular graft for reconstruction of osseous defects after resection of primary malignant bone tumors,” Orthopade, vol. 32, no. 11, pp. 983–993, 2003. View at Publisher · View at Google Scholar · View at Scopus
  38. J. Hennen, D. Sabo, A. K. Martini, and L. Bernd, “Combined vascularized fibula and allograft shell after resection of primary malignant bone tumors of the lower limb,” Unfallchirurg, vol. 105, no. 2, pp. 120–127, 2002. View at Publisher · View at Google Scholar · View at Scopus
  39. T. Ozaki, A. Hillmann, P. Wuisman, and W. Winkelmann, “Reconstruction of tibia by ipsilateral vascularized fibula and allograft. 12 cases with malignant bone tumors,” Acta Orthopaedica Scandinavica, vol. 68, no. 3, pp. 298–301, 1997. View at Scopus
  40. A. H. Krieg and F. Hefti, “Reconstruction with non-vascularised fibular grafts after resection of bone tumours,” Journal of Bone and Joint Surgery B, vol. 89, no. 2, pp. 215–221, 2007. View at Publisher · View at Google Scholar · View at Scopus
  41. S. Shalaby, H. Shalaby, and A. Bassiony, “Limb salvage for osteosarcoma of the distal tibia with resection arthrodesis, autogenous fibular graft and Ilizarov external fixator,” Journal of Bone and Joint Surgery B, vol. 88, no. 12, pp. 1642–1646, 2006. View at Publisher · View at Google Scholar · View at Scopus
  42. S. A. Hanna, M. D. Sewell, W. J. S. Aston et al., “Femoral diaphyseal endoprosthetic reconstruction after segmental resection of primary bone tumours,” Journal of Bone and Joint Surgery B, vol. 92, no. 6, pp. 867–874, 2010. View at Publisher · View at Google Scholar · View at Scopus
  43. P. Ruggieri, A. F. Mavrogenis, G. Bianchi, V. I. Sakellariou, M. Mercuri, and P. J. Papagelopoulos, “Outcome of the intramedullary diaphyseal segmental defect fixation system for bone tumors,” Journal of Surgical Oncology, vol. 104, pp. 83–90, 2011. View at Publisher · View at Google Scholar
  44. A. Abudu, S. R. Carter, and R. J. Grimer, “The outcome and functional results of diaphyseal endoprostheses after tumour excision,” Journal of Bone and Joint Surgery B, vol. 78, no. 4, pp. 652–657, 1996. View at Scopus
  45. E. Aldlyami, A. Abudu, R. J. Grimer, S. R. Carter, and R. M. Tillman, “Endoprosthetic replacement of diaphyseal bone defects. Long-term results,” International Orthopaedics, vol. 29, no. 1, pp. 25–29, 2005. View at Publisher · View at Google Scholar · View at Scopus
  46. E. R. Ahlmann and L. R. Menendez, “Intercalary endoprosthetic reconstruction for diaphyseal bone tumours,” Journal of Bone and Joint Surgery B, vol. 88, no. 11, pp. 1487–1491, 2006. View at Publisher · View at Google Scholar · View at Scopus
  47. J. S. Wunder, J. H. Healey, A. M. Davis, and M. F. Brennan, “A comparison of staging systems for localized extremity soft tissue sarcoma,” Cancer, vol. 88, pp. 2721–2730, 2000.
  48. E. J. Fox, M. A. Hau, M. C. Gebhardt, F. J. Hornicek, W. W. Tomford, and H. J. Mankin, “Long-term followup of proximal femoral allografts,” Clinical Orthopaedics and Related Research, no. 397, pp. 106–113, 2002. View at Scopus
  49. F. J. Hornicek, M. C. Gebhardt, J. I. Sorger, and H. J. Mankin, “Tumor reconstruction,” Orthopedic Clinics of North America, vol. 30, no. 4, pp. 673–684, 1999. View at Publisher · View at Google Scholar · View at Scopus
  50. H. J. Mankin, D. S. Springfield, M. C. Gebhardt, and W. W. Tomford, “Current status of allografting for bone tumors,” Orthopedics, vol. 15, no. 10, pp. 1147–1154, 1992. View at Scopus
  51. H. J. Mankin, M. C. Gebhardt, L. C. Jennings, D. S. Springfield, and W. W. Tomford, “Long-term results of allograft replacement in the management of bone tumors,” Clinical Orthopaedics and Related Research, no. 324, pp. 86–97, 1996. View at Scopus
  52. M. Manfrini, A. Gasbarrini, C. Malaguti et al., “Intraepiphyseal resection of the proximal tibia and its impact on lower limb growth,” Clinical Orthopaedics and Related Research, no. 358, pp. 111–119, 1999. View at Scopus
  53. M. C. Gebhardt, D. I. Flugstad, D. S. Springfield, and H. J. Mankin, “The use of bone allografts for limb salvage in high-grade extremity osteosarcoma,” Clinical Orthopaedics and Related Research, no. 270, pp. 181–196, 1991. View at Scopus
  54. B. H. Berrey, C. F. Lord, M. C. Gebhardt, and H. J. Mankin, “Fractures of allografts. Frequency, treatment, and end-results,” Journal of Bone and Joint Surgery A, vol. 72, no. 6, pp. 825–833, 1990. View at Scopus
  55. D. Donati, M. Di Liddo, M. Zavatta et al., “Massive bone allograft reconstruction in high-grade osteosarcoma,” Clinical Orthopaedics and Related Research, no. 377, pp. 186–194, 2000. View at Scopus
  56. J. W. Wang and C. H. Shih, “Allograft transplantation in aggressive or malignant bone tumors,” Clinical Orthopaedics and Related Research, no. 297, pp. 203–209, 1993. View at Scopus
  57. W. F. Enneking and D. A. Campanacci, “Retrieved human allografts. A clinicopathological study,” Journal of Bone and Joint Surgery A, vol. 83, no. 7, pp. 971–986, 2001. View at Scopus
  58. W. F. Enneking and E. R. Mindell, “Observations on massive retrieved human allografts,” Journal of Bone and Joint Surgery A, vol. 73, no. 8, pp. 1123–1142, 1991. View at Scopus
  59. D. W. Chang and K. L. Weber, “Segmental femur reconstruction using an intercalary allograft with an intramedullary vascularized fibula bone flap,” Journal of Reconstructive Microsurgery, vol. 20, no. 3, pp. 195–199, 2004. View at Publisher · View at Google Scholar · View at Scopus
  60. K. Bakri, A. A. Stans, S. Mardini, and S. L. Moran, “Combined massive allograft and intramedullary vascularized fibula transfer: the capanna technique for lower-limb reconstruction,” Seminars in Plastic Surgery, vol. 22, pp. 234–241, 2008. View at Publisher · View at Google Scholar