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Sarcoma
Volume 2013 (2013), Article ID 360214, 6 pages
http://dx.doi.org/10.1155/2013/360214
Clinical Study

Safety and Efficacy of Stereotactic Body Radiation Therapy in the Treatment of Pulmonary Metastases from High Grade Sarcoma

1Department of Radiation Oncology, David Geffen School of Medicine at UCLA, 200 UCLA Medical Plaza, B265, Los Angeles, CA 90095, USA
2UCLA Jonsson Comprehensive Cancer Center, 10833 Le Conte Ave, Los Angeles, CA 90095, USA
3Division of Pediatric Hematology Oncology, Department of Pediatrics, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
4Division of Thoracic Surgery, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
5Division of Surgical Oncology, Department of Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
6Division of Hematology Oncology, Department of Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA

Received 8 May 2013; Revised 7 August 2013; Accepted 30 August 2013

Academic Editor: Cyril Fisher

Copyright © 2013 Niraj Mehta et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Linked References

  1. Z. Kon and L. Martin, “Resection for thoracic metastases from sarcoma,” Oncology, vol. 25, no. 12, pp. 1198–1204, 2011. View at Scopus
  2. M. F. Brennan, E. S. Casper, L. B. Harrison, M. H. Shiu, J. Gaynor, and S. I. Hajdu, “The role of multimodality therapy in soft-tissue sarcoma,” Annals of Surgery, vol. 214, no. 3, pp. 328–338, 1991. View at Scopus
  3. P. W. T. Pisters, L. B. Harrison, D. H. Y. Leung, J. M. Woodruff, E. S. Casper, and M. F. Brennan, “Long-term results of a prospective randomized trial of adjuvant brachytherapy in soft tissue sarcoma,” Journal of Clinical Oncology, vol. 14, no. 3, pp. 859–868, 1996. View at Scopus
  4. D. A. Potter, T. Kinsella, and E. Glatstein, “High-grade soft tissue sarcomas of the extremities,” Cancer, vol. 58, no. 1, pp. 190–205, 1986. View at Scopus
  5. M. van Glabbeke, A. T. van Oosterom, J. W. Oosterhuis et al., “Prognostic factors for the outcome of chemotherapy in advanced soft tissue sarcoma: An analysis of 2,185 patients treated with anthracycline-containing first-line regimens—a European organization for research and treatment of cancer soft tissue and bone sarcoma group study,” Journal of Clinical Oncology, vol. 17, no. 1, pp. 150–157, 1999. View at Scopus
  6. K. G. Billingsley, M. E. Burt, E. Jara et al., “Pulmonary metastases from soft tissue sarcoma: analysis of patterns of disease and postmetastasis survival,” Annals of Surgery, vol. 229, no. 5, pp. 602–612, 1999. View at Publisher · View at Google Scholar · View at Scopus
  7. U. Pastorino, “Lung metastasectomy: why, when, how,” Critical Reviews in Oncology/Hematology, vol. 26, no. 3, pp. 137–145, 1997. View at Publisher · View at Google Scholar · View at Scopus
  8. A. G. Casson, J. B. Putnam, G. Natarajan et al., “Five-year survival after pulmonary metastasectomy for adult soft tissue sarcoma,” Cancer, vol. 69, no. 3, pp. 662–668, 1992. View at Scopus
  9. J. B. Putnam Jr., J. A. Roth, and M. N. Wesley, “Analysis of prognostic factors in patients undergoing resection of pulmonary metastases from soft tissue sarcomas,” Journal of Thoracic and Cardiovascular Surgery, vol. 87, no. 2, pp. 260–268, 1984. View at Scopus
  10. J. A. Roth, J. B. Putnam Jr., M. N. Wesley, and S. A. Rosenberg, “Differing determinants of prognosis following resection of pulmonary metastases from osteogenic and soft tissue sarcoma patients,” Cancer, vol. 55, no. 6, pp. 1361–1366, 1985. View at Scopus
  11. R. Smith, Y. Pak, W. Kraybill, and J. M. Kane III, “Factors associated with actual long-term survival following soft tissue sarcoma pulmonary metastasectomy,” European Journal of Surgical Oncology, vol. 35, no. 4, pp. 356–361, 2009. View at Publisher · View at Google Scholar · View at Scopus
  12. M. A. Gadd, E. S. Casper, J. M. Woodruff, P. M. McCormack, and M. F. Brennan, “Development and treatment of pulmonary metastases in adult patients with extremity soft tissue sarcoma,” Annals of Surgery, vol. 218, no. 6, pp. 705–712, 1993. View at Scopus
  13. A. Rehders, S. B. Hosch, P. Scheunemann, N. H. Stoecklein, W. T. Knoefel, and M. Peiper, “Benefit of surgical treatment of lung metastasis in soft tissue sarcoma,” Archives of Surgery, vol. 142, no. 1, pp. 70–76, 2007. View at Publisher · View at Google Scholar · View at Scopus
  14. M. R. Weiser, R. J. Downey, D. H. Y. Leung, and M. F. Brennan, “Repeat resection of pulmonary metastases in patients with soft-tissue sarcoma,” Journal of the American College of Surgeons, vol. 191, no. 2, pp. 184–191, 2000. View at Publisher · View at Google Scholar · View at Scopus
  15. E. T. Creagan, T. R. Fleming, J. H. Edmonson, and P. C. Pairolero, “Pulmonary resection for metastatic nonosteogenic sarcoma,” Cancer, vol. 44, no. 5, pp. 1908–1912, 1979. View at Scopus
  16. A. N. van Geel, U. Pastorino, K. W. Jauch, et al., “Surgical treatment of lung metastases: the European Organization for Research and Treatment of Cancer-Soft Tissue and Bone Sarcoma Group study of 255 patients,” Cancer, vol. 77, pp. 675–682, 1996.
  17. R. Timmerman, R. Paulus, J. Galvin et al., “Stereotactic body radiation therapy for inoperable early stage lung cancer,” Journal of the American Medical Association, vol. 303, no. 11, pp. 1070–1076, 2010. View at Publisher · View at Google Scholar · View at Scopus
  18. N. Mehta, C. R. King, N. Agazaryan, M. Steinberg, A. Hua, and P. Lee, “Stereotactic body radiation therapy and 3-dimensional conformal radiotherapy for stage I non-small cell lung cancer: a pooled analysis of biological equivalent dose and local control,” Practical Radiation Oncology, vol. 2, no. 4, pp. 288–295, 2012. View at Publisher · View at Google Scholar · View at Scopus
  19. M. T. Milano, A. W. Katz, A. G. Muhs et al., “A prospective pilot study of curative-intent stereotactic body radiation therapy in patients with 5 or fewer oligometastatic lesions,” Cancer, vol. 112, no. 3, pp. 650–658, 2008. View at Publisher · View at Google Scholar · View at Scopus
  20. K. E. Rusthoven, B. D. Kavanagh, S. H. Burri et al., “Multi-institutional phase I/II trial of stereotactic body radiation therapy for lung metastases,” Journal of Clinical Oncology, vol. 27, no. 10, pp. 1579–1584, 2009. View at Publisher · View at Google Scholar · View at Scopus
  21. R. Timmerman, R. McGarry, C. Yiannoutsos et al., “Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer,” Journal of Clinical Oncology, vol. 24, no. 30, pp. 4833–4839, 2006. View at Publisher · View at Google Scholar · View at Scopus
  22. J. F. Fowler, “The linear-quadratic formula and progress in fractionated radiotherapy,” British Journal of Radiology, vol. 62, no. 740, pp. 679–694, 1989. View at Scopus
  23. L. Erhunmwunsee and T. A. D'Amico, “Surgical management of pulmonary metastases,” Annals of Thoracic Surgery, vol. 88, no. 6, pp. 2052–2060, 2009. View at Publisher · View at Google Scholar · View at Scopus
  24. S. Dhakal, K. S. Corbin, M. T. Milano et al., “Stereotactic body radiotherapy for pulmonary metastases from soft-tissue sarcomas: excellent local lesion control and improved patient survival,” International Journal of Radiation Oncology Biology Physics, vol. 82, no. 2, pp. 940–945, 2012. View at Publisher · View at Google Scholar · View at Scopus
  25. R. B. Barriger, J. A. Forquer, J. G. Brabham et al., “A dose-volume analysis of radiation pneumonitis in non-small cell lung cancer patients treated with stereotactic body radiation therapy,” International Journal of Radiation Oncology Biology Physics, vol. 82, no. 1, pp. 457–462, 2012. View at Publisher · View at Google Scholar · View at Scopus
  26. M. Guckenberger, K. Heilman, J. Wulf, G. Mueller, G. Beckmann, and M. Flentje, “Pulmonary injury and tumor response after stereotactic body radiotherapy (SBRT): results of a serial follow-up CT study,” Radiotherapy and Oncology, vol. 85, pp. 435–442, 2007.
  27. J. S. A. Belderbos, W. D. Heemsbergen, K. de Jaeger, P. Baas, and J. V. Lebesque, “Final results of a Phase I/II dose escalation trial in non-small-cell lung cancer using three-dimensional conformal radiotherapy,” International Journal of Radiation Oncology Biology Physics, vol. 66, no. 1, pp. 126–134, 2006. View at Publisher · View at Google Scholar · View at Scopus
  28. J. Bradley, M. V. Graham, K. Winter et al., “Toxicity and outcome results of RTOG 9311: a phase I-II dose-escalation study using three-dimensional conformal radiotherapy in patients with inoperable non-small-cell lung carcinoma,” International Journal of Radiation Oncology Biology Physics, vol. 61, no. 2, pp. 318–328, 2005. View at Publisher · View at Google Scholar · View at Scopus
  29. S. Kim, H. C. Ott, C. D. Wright et al., “Pulmonary resection of metastatic sarcoma: prognostic factors associated with improved outcomes,” Annals of Thoracic Surgery, vol. 92, no. 5, pp. 1780–1787, 2011. View at Publisher · View at Google Scholar · View at Scopus
  30. P. Okunieff, A. L. Petersen, A. Philip et al., “Stereotactic Body Radiation Therapy (SBRT) for lung metastases,” Acta Oncologica, vol. 45, no. 7, pp. 808–817, 2006. View at Publisher · View at Google Scholar · View at Scopus