Reduced Latency in the Metastatic Niche Contributes to the More Aggressive Phenotype of LM8 Compared to Dunn Osteosarcoma Cells

Table 1

Number of regulated (>2-fold; P < 0.05) Dunn/LM8 gene sets enriched in KEGG pathways (DAVID).

Pathways	Gene count	%^1
Pathways in cancer	31	3.78
Focal adhesion	22	2.68
Cytokine-cytokine receptor interaction	19	2.31
Regulation of actin cytoskeleton	16	1.95
Axon guidance	14	1.71
Cell adhesion molecules (CAMs)	14	1.71
Vascular smooth muscle contraction	11	1.34
ECM-receptor interaction	10	1.22
Apoptosis	9	1.10
Basal cell carcinoma	8	0.97
Complement and coagulation cascades	8	0.97
Adherens junction	8	0.97
Hematopoietic cell lineage	8	0.97
Hedgehog signaling pathway	7	0.85
Glutathione metabolism	6	0.73
Prion diseases	5	0.61
Glycosphingolipid biosynthesis	4	0.49

1Proportion of all regulated gene sets.