Insulin-Like Growth Factor 1 Receptor as a Therapeutic Target in Ewing Sarcoma: Lack of Consistent Upregulation or Recurrent Mutation and a Review of the Clinical Trial Literature

Table 1

Ligand-binding displacement quantification of IGF-1R surface expression in ES cell lines. The column adjacent to cell line names refers to replicate experiments.

Cell Line		𝐾𝑑 (M)	Receptor number per cell
A4573	1	2.80×10^−10	16895
	2	1.81×10^−10	13163
ES-5838	1	2.69×10^−10	27274
	2	2.23×10^−10	14095
SK-N-MC	1	3.24×10^−10	27519
	2	4.58×10^−10	40424
TC71		2.37×10^−10	25156