Figure 4: OS cell migration and invasion is sensitive to rapamycin treatment. (a) K7M2 and K12 cell migration was tracked in the presence or absence (DMSO only control) of rapamycin (10 μM) and the data obtained is displayed. (b) The velocity of cell migration was determined in each group in (a) and the results are displayed. (c) K7M2 cell invasion through a 2.5% Matrigel was monitored for 18 hours in the presence or absence (DMSO only) of 10 μM rapamycin. Asterisks (*) indicate statistically significant differences ().