Research Article

Cost Effectiveness of First-Line Treatment with Doxorubicin/Ifosfamide Compared to Trabectedin Monotherapy in the Management of Advanced Soft Tissue Sarcoma in Italy, Spain, and Sweden

Table 5

Unit resource costs (in Euros at 2010/2011 prices) used in the model.

ResourceUnit costs (in Euros at 2010/2011 prices)
ItalySpainSweden

Aprepitant (125 mg)€90.9[72]€63.8[73]
Betapred (4 mg)€6.4[73]
Betamethasone (8 mg)€3.2[73]
Biopsy€129.1[74]€603.7[75]€314.1[76]
Bone scintigraphy €296.8[77]
Chest X-ray€16.2[78]€6.5[79]€48.7[76]
CT scan€86.3[74]€87.5[79]€313.6[76]
Cyclophosphamide (200 mg)€4.1[80]
Dacarbazine (1000 mg)€21.7[80]
Dacarbazine (200 mg)€8.9[80]
Dexamethasone (0.75 mg, 10 tablets)€1.1[81]
Dexamethasone (1 mg, 30 tablets)€3.0[72]
Diphenhydramine (25 mg, 25 capsules)€1.4[72]
Docetaxel (10 mg)€84.4[80]
Docetaxel (100 mg)€182.8[80]
Docetaxel (80 mg)€403.1[80]
Doxorubicin (50 mg)€119.5[80] €4.1[80]€59.8[80]
Echocardiography€51.7[74]€18.2[79]€214.9[76]
Electrocardiogram€13.0[78]€13.5[82]€334.2[76]
Epirubicin (50 mg)€81.2[80]
Etoposide (100 mg)€20.8[80]
Filgrastim (300 mcg)€94.8[72]
Filgrastim (6 mg)€149.8[81]
Gemcitabine (1000 mg)€113.2[80]€75.7[80]€104.6[80]
General surgeon consultation€230.3[76]
Granisetron (1 mg, 10 tablets)€133.9[81]€48.1[72]
Haematology tests€3.7[83]€20.5[82]€5.2[76]
Hospitalisation for chemotherapy infusion/day€238.3[84]€212.9[84]€288.6[84]
Ifosfamide (1 g)€30.7[80]€19.7[80]
Ifosfamide (2 g)€65.7[80]
Lenograstim (1 vial)€153.4[81]
Levocetirizine (5 mg, 20 tablets)€10.5[81]
Liver function test€9.2[83]€11.7[79]
Liposomal doxorubicin (2 mg)€548.2[80]
Managing anaemia€1,354.8[85]€900.0[86]€548.6[87]
Managing febrile neutropenia€3,305.0[88]€3829.5 [89]€2,892.0[90]
Managing neutropenia€523.3[85]€2086.1[91]
Managing thrombocytopenia€1,354.8[85]€900.0[86]€548.6[87]
Mesna (3 g)€13.2[72]
Mesna (6 g)€25.7[81]
Mesna (5 g)€192.2[73]
Metoclopramide (250 mL)€2.7[72]
MRI scan€285.8[83]€168.0[79]€386.4[76]
Multidisciplinary team assessment€48.7[74]€61.3[79]€1,816.5[76]
Nuclear medicine specialist consultation€61.5[79]
Nurse home visit €51.2[92]€56.5[77]
Oncologist consultation€21.6[83]€61.5[79]€283.7[76]
Ondansetron (4 mg, 6 tablets)€57.8[81]
Ondansetron (4 mg, 15 tablets)€36.3[72]
Orthopaedic surgeon consultation€21.6[83]€61.5[79]€102.4[76]
Outpatient attendance for chemotherapy€122.8[84]€98.9[84]€288.6[84]
Paclitaxel (30 mg)€83.8[80]
Palliative care per patient€3,265.0[93]€2167.7[94]€1,343.9[95, 96]
Palonosetron (250 mcg)€104.6[72]
Pathologist consultation€21.6[83]€61.5[79]
Pegfilgrastim (1 syringe)€1,062.6[72]€1,322.5[73]
PET scan€1,071.7[74]€500.0[79]€314.1[76]
Radiologist consultation€21.6[83]€61.5[79]
Radiotherapist consultation€21.6[83]€61.5[79]
Renal function test€5.0[83]€8.9[79]
Secondary care hospital specialist visit€61.5[79]
Trabectedin (1 mg, 1 vial)€2,970.1[80]€2,049.9[80]€1,913.3[80]
Trofosfamide 50 mg/m2€1.4[80]
Tropisetron (5 mg)€20.5[73]
Ultrasound scan€17.6[74]€18.2[79]
Urine analysis€6.1[83]€1.8[79]€20.9[76]
Vincristine (1 mg)€16.2[80]
Vinorelbine (1 mL)€24.1[80]

In Sweden unit costs were converted from Swedish Krona (SEK) to Euros at the rate of €1 = 9.55 SEK.