Research Article

Sporadic versus Radiation-Associated Angiosarcoma: A Comparative Clinicopathologic and Molecular Analysis of 48 Cases

Table 3

Immunohistochemical and mutational analysis of prognostic markers comparing sporadic angiosarcomas (SA) and radiation-associated angiosarcomas (RAA).

p53 overexpressionKi-67 hTERT TP53
mutation
ATM
mutation
<50%≥50%

SA9/35
(25.7%)
22/34
(64.7%)
12/34
(35.3%)
37/37
(100%)
5/37 (13.5%)0/37
(0%)

RAA0/9
(0%)
5/9
(55.6%)
4/9
(44.4%)
9/9
(100%)
1/9
(11.1%)
0/9
(0%)